Analysis of positive or negative regulatory mechanism for thrombus formation

血小板功能在正负调节因子的平衡中调节。在这项研究中，我们的特点是ADP受体P2 Y12，胶原受体GPVI，血栓烷A2受体作为这些受体异常患者的正调节剂。感兴趣的是，P2 Y12介导的信号传导在持续的免疫应答中起着关键作用。IIb. 3激活。当然，我们演示过了。-辅肌动蛋白起负调节和负调节作用。IIb. 3激活。

Platelet function is regulated in the balance of positive and negative regulators. In this study, we have characterized ADP receptor P2Y12, collagen receptor GPVI, and thromboxane A2 receptor as positive regulators in patients with abnormality of these receptors. Of interest is that P2Y12-mediated signaling plays a critical role in the sustained. IIb. 3 activation. Inversely, we demonstrayed that.-actinin plays as a negative regulator and negatively regulate. IIb. 3 activation.