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Imaging diagnosis of multi-step hepatocarcinogenesis : clinical and basic analysis

Imaging diagnosis of multi-step hepatocarcinogenesis : clinical and basic analysis
多步肝癌的影像诊断:临床与基础分析
批准号:
21591549
负责人:
MATSUI Osamu
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

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中文摘要
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英文摘要
In accordance with the progression of multi-step hepatocarcinogenesis, the drainage vessels from the tumor changed from hepatic vein to hepatic sinusoids, and then portal vein, and this can be diagnosed by dynamic CT. There was an intensely significant correlation between OATP8 expression and signal intensity on hepatobiliary phase of Gd-EOB-DTPA enhanced MRI. In addition, the expression of OATP8 was decreased from very early stage of hepatocarcinogenesis in accordance with the elevation of grade of malignancy of the tumors. Therefore, EOB-MRI was proved to be extremely useful in the diagnosis of early HCC
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会议论文
教育講演「肝腫瘍」
教育讲座“肝脏肿瘤”
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Mita A, Urata K, 松井修]
通讯作者: 松井修
DOI: 10.1038/labinvest.2010.161
发表时间: 2011-02-01
期刊: LABORATORY INVESTIGATION
影响因子: 5
作者: [Yoneda, Norihide, Sato, Yasunori, Nakanuma, Yasuni]
通讯作者: Nakanuma, Yasuni
Diagnostic challenge of very early stage HCC : Evaluation of hepato-carcinogenesis with Gd-EOB-DTPA enhanced MRI : correlation with histopathology and transporter expression
极早期 HCC 的诊断挑战:用 Gd-EOB-DTPA 增强 MRI 评估肝癌发生:与组织病理学和转运蛋白表达的相关性
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [大野康成, 浦田浩一, 工藤崇, 松井修]
通讯作者: 松井修
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Kitao A, Zen Y, Matsui O, et al.]
通讯作者: et al.
30
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    • 资助金额:
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      1999
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