Imaging diagnosis of multi-step hepatocarcinogenesis : clinical and basic analysis
Imaging diagnosis of multi-step hepatocarcinogenesis : clinical and basic analysis
批准号:
21591549
负责人:
MATSUI Osamu
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
In accordance with the progression of multi-step hepatocarcinogenesis, the drainage vessels from the tumor changed from hepatic vein to hepatic sinusoids, and then portal vein, and this can be diagnosed by dynamic CT. There was an intensely significant correlation between OATP8 expression and signal intensity on hepatobiliary phase of Gd-EOB-DTPA enhanced MRI. In addition, the expression of OATP8 was decreased from very early stage of hepatocarcinogenesis in accordance with the elevation of grade of malignancy of the tumors. Therefore, EOB-MRI was proved to be extremely useful in the diagnosis of early HCC
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教育講演「肝腫瘍」
教育讲座“肝脏肿瘤”
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Mita A, Urata K, 松井修]
通讯作者:
松井修
DOI:
10.1038/labinvest.2010.161
发表时间:
2011-02-01
期刊:
LABORATORY INVESTIGATION
影响因子:
5
作者:
[Yoneda, Norihide, Sato, Yasunori, Nakanuma, Yasuni]
通讯作者:
Nakanuma, Yasuni
Diagnostic challenge of very early stage HCC : Evaluation of hepato-carcinogenesis with Gd-EOB-DTPA enhanced MRI : correlation with histopathology and transporter expression
极早期 HCC 的诊断挑战:用 Gd-EOB-DTPA 增强 MRI 评估肝癌发生:与组织病理学和转运蛋白表达的相关性
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[大野康成, 浦田浩一, 工藤崇, 松井修]
通讯作者:
松井修
Organicanion transporting polypepride8 expression correlates with the signal intensity of hepatocellular carcinoma on hepatobiliary phase of Gd-EOB-DTPA enhanced MRI
有机阴离子转运多肽8表达与肝细胞癌Gd-EOB-DTPA增强MRI肝胆期信号强度相关
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Kitao A, Zen Y, Matsui O, et al.]
通讯作者:
et al.
Organic anion transporting polypepride8 expression correlates with the signal intensity of hepatocellular carcinoma on hepatobiliary phase of Gd-EOB-GTPA enhanced MRI
有机阴离子转运多肽8表达与肝细胞癌Gd-EOB-GTPA增强MRI肝胆相信号强度相关
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Kitao A, Zen Y, Matsui O, et al]
通讯作者:
et al
共 30 条
In vivo analysis of the effect of antiangiogenic drug on hepatocarcinogenesis
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批准号:18591332
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.48万
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财政年份:2006
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负责人:MATSUI Osamu
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依托单位:
Multi-step hepatocarcinogenesis and neovascularization-Observation by vital microscopy
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批准号:14570841
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.5万
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财政年份:2002
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负责人:MATSUI Osamu
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依托单位:
Development of nitinol-based stent-graft for the treatment of aortic aneurysms : with special reference to a thin and flexible stent-graft system.
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批准号:11670875
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.43万
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财政年份:1999
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负责人:MATSUI Osamu
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依托单位:
Correlation between the intranodular blood supply and the grade of malignancy of hepatocellular nodules associated with liver cirrhosis
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批准号:09670920
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.15万
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财政年份:1997
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负责人:MATSUI Osamu
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依托单位:
The Stufy of the Effect of Hepatic Copper Content on Signal Intensity in Magnetic Reasonance Images
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批准号:04670662
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$0.9万
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财政年份:1992
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负责人:MATSUI Osamu
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依托单位:
Experimental study on the transcatheter proximal arterial occlusion maintaining the blood supply to the distal organs.
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批准号:02807102
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$0.96万
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财政年份:1990
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负责人:MATSUI Osamu
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依托单位: