Development of small-diameter vascular graft composed of antithrombogenic phospholipid polymer

使用MPC涂层和无涂层ePTFE移植物的颈动脉或股动脉旁路术的通畅率在1周后分别为9/37（24%）和14/37（38%）; 2周后分别为4/37（11%）和6/37（15%）; 4周后分别为3/37（8%）和3/37（8%）。根据组织学检查，血栓附着在宿主动脉的切割边缘。与未涂层移植物相比，吻合口处的内膜增生和MPC涂层移植物表面没有显着变化。

The patency rates of carotid or femoral arterial bypass with MPC-coated and noncoated ePTFE grafts were 9/37(24%) and 14/37(38%) after one week ; 4/37(11%) and 6/37(15%) after two weeks ; and 3/37(8%) and 3/37(8%) after four weeks. Based on a histological examination, the thrombus was attached to the cut edges of the host artery. Intimal hyperplasia at the anastomosis and the surface of MPC-coated grafts was not changed remarkably compared with noncoated grafts.