Establishment of rapid Intraoperative Detection of Lymph Node metastasis Using Molecularbiological Method

分子生物学方法术中快速检测淋巴结转移的建立

• 批准号: 21591818
• 负责人: SHIRAISHI Kenji
• 金额: $ 3万
• 依托单位: Kumamoto University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21591818/
• 关键词: TRC法; リンパ節転移; 肺癌

To improve the results of surgical treatment for lung cancer, a molecular biological TRC method(Transcription Reverse transcription Concerted reaction) was carried out to quantify the messenger RNA level of CEA. This method have high sensitivity in detecting the presence of cancer cells, but more investigation need to verify the accuracy of this method, for exsample, the matching of the result with histopathological diagnosis.

为了提高肺癌手术治疗效果，采用分子生物学TRC方法（转录逆转录协同反应）对CEA的信使RNA水平进行定量。该方法在检测癌细胞的存在方面具有较高的灵敏度，但需要更多的研究来验证该方法的准确性，例如结果与组织病理学诊断的匹配。