A comparative study of the bone forming ability of surface-treated porous titanium materials

表面处理多孔钛材料成骨能力的对比研究

• 批准号: 21591898
• 负责人: NEO Masashi
• 金额: $ 3.08万
• 依托单位: Kyoto University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21591898/
• 关键词: 生体活性; チタン; 脊椎; インプラント; 固定術; 骨誘導

We investigated the effect of the surface treatment on the bone forming abilities of porous titanium implant in the long term. Three types of surface treatments were applied :(a) hydroxyapatite coating(HA),(b) alkali, hot water, and heat treatment(AW), and(c) alkali, dilute HCl, hot water, and heat treatment(HCl). We then examined the amount of bone formation within the materials implanted in the femoral condyles of Japanese white rabbits at 6, 12, 26, 52, and 104 weeks. The results showed that the bone ingrowth in AW and HCl was significantly higher than in HA after 52 and after 12 weeks, respectively.

长期观察表面处理对多孔钛种植体成骨能力的影响。采用了三种类型的表面处理：(A)羟基磷灰石涂层(HA)，(B)碱、热水和热处理(AW)，和(C)碱、稀盐酸、热水和热处理(HCl)。然后，我们检测了6周、12周、26周、52周和104周时植入日本大白兔股骨髁内的骨形成量。结果表明，AW组和HCl组在植入52周和12周后的骨长入明显高于HA组。