A study of injectable osteoconductive bone substitute materials

点击翻译按钮获取中文摘要

Octacalcium phosphate(OCP)crystals, having particular stoichiometeric composition, have been shown to display a stimulatory capacity on osteoblastic differentiation and bone regeneration. Synthesized OCP crystals show higher biocompatibility and are expected to be an artificial bioabsorbable material. On the other hand, its brittleness based on the ceramics characteristics makes it difficult to mold the objective shape. In the present study, we created a new OCP materials combined with hyaluronan(Hya), which could be used as the injectable form, and examined their bone regenerative properties on mouse calvaria.