The approach to a trigeminal neuralgia mechanism based on a local GABA system hypothesis
The approach to a trigeminal neuralgia mechanism based on a local GABA system hypothesis
批准号:
21591990
负责人:
HAYASAKI Hana
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
We investigated possibility of the neural transmission regulation of the SC-nerve cell by imaging of extracellular GABA release at the trigeminal ganglion.As a result, GABA was released both from neuron and SG on dispersion culture, and the GABA release of neuron was inhibited by GAT inhibitor(nipecotic acid), and GABA release of SG was inhibited by anion channel inhibitor(DNDS).As a result, GABA was released both from neuron and SG on dispersion culture, and the GABA release of neuron was inhibited by GAT inhibitor(nipecotic acid), and GABA release of SG was inhibited by anion channel inhibitor(DNDS).
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DOI:
10.1016/j.neures.2010.12.010
发表时间:
2011-04
期刊:
Neuroscience Research
影响因子:
2.9
作者:
[Taku Uchida;Y. Oki;Y. Yanagawa;A. Fukuda]
通讯作者:
Taku Uchida;Y. Oki;Y. Yanagawa;A. Fukuda
GABA handling system in the rat trigeminal ganglion
大鼠三叉神经节中的 GABA 处理系统
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Shimizu H, Yu YC, Kono K, Kubota T, Yasui M, Li M, Hwang TC, Sohma Y, 早崎華]
通讯作者:
早崎華
A stable ATP binding to nucleotide binding domain is important for reliable gating cycle in an ABC transporter CFTR
ATP 与核苷酸结合域的稳定结合对于 ABC 转运蛋白 CFTR 中可靠的门控循环非常重要
DOI:
--
发表时间:
2010
期刊:
Journal of Physiological Sciences
影响因子:
2.3
作者:
[Shimizu H, Yu YC, Sohma Y, et al]
通讯作者:
et al
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[C. Stewart;A. Touraev;V. Citovsky;T. Tzfira]
通讯作者:
C. Stewart;A. Touraev;V. Citovsky;T. Tzfira
An immunocytochemical study for the local GABAergic system in rat trigeminal ganglion
大鼠三叉神经节局部 GABA 能系统的免疫细胞化学研究
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Hayasaki H, Morishima T, Sohma Y, Yoshida S, Fukuda A, Otsuki A]
通讯作者:
Otsuki A
共 6 条
Inhibitory effect of GABA in excitatory sensory ganglia
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批准号:19591824
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.33万
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财政年份:2007
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负责人:HAYASAKI Hana
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依托单位:
海外基金