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Mechanism of tumor regulation by galactose-binding protein in hormone refractory prostate cancer

Mechanism of tumor regulation by galactose-binding protein in hormone refractory prostate cancer
半乳糖结合蛋白在激素难治性前列腺癌中的肿瘤调控机制
批准号:
21592048
负责人:
FUKUMORI Tomoharu
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

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中文摘要
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英文摘要
Galectin-3, has been strongly expressed in hormone-refractory prostate cancer, showed a negative correlation between expression of androgen receptor and galectin-3 in hormone-refractory prostate cancer cell line PC3. Galectin-3 was involved in resistance to apoptosis induced by platinum-based drug and radio therapy through the suppression of the caspase-3 activity and stability of the mitochondria. Galectin-3 is a target protein involved in the resistance of hormone therapy, chemotherapy and radiotherapy in hormone-refractory prostate cancer.
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DOI: 10.2152/jmi.57.152
发表时间: 2010-02-01
期刊: JOURNAL OF MEDICAL INVESTIGATION
影响因子: 0.7
作者: [Sakaki, Manabu, Fukumori, Tomoharu, Kanayama, Hiro-Omi]
通讯作者: Kanayama, Hiro-Omi
前立腺癌I-125密封小線源療法におけるネオアジュバンド内分泌療法の有用性
新辅助内分泌治疗在前列腺癌 I-125 近距离放射治疗中的应用
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [湯浅健, 羽渕友則, 湯浅健, Shiirevnyamba A, Takahiro Koizumi, Sakaki M, Nakanishi R, アビルメド・シーレンヤンバ, 中逵弘能, 松村英理, 中逵弘能, 松村英理, S Avirmed, 中逵弘能, 中逵弘能, 福森知治, 福森知治]
通讯作者: 福森知治
DOI: 10.1016/j.urology.2009.09.037
发表时间: 2010-02-01
期刊: UROLOGY
影响因子: 2.1
作者: [Koizumi, Takahiro, Nakatsuji, Hiroyoshi, Kanayama, Hiroomi]
通讯作者: Kanayama, Hiroomi
Participation of N-caderin in bladder cancer
N-caderin参与膀胱癌的发生
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [久末伸一, 井手久満, 吉井 隆, 知名俊幸, 磯谷周治, 斉藤恵介, 小関達郎, 常盤紫野, 永栄美香, 山口雷蔵, 武藤 智, 堀江重郎, S Avirmed,Uehara H,Nakatsiji H,Fukawa T,Takemura M,Yamamoto Y,Yamaguchi K Kishimot T,Izaki H,Takahashi M,Fukumori T,Kanayama H, 久末伸一, S Avilmed, Shin-ichi Hisasue, アビルメド・シーレンヤンバ]
通讯作者: アビルメド・シーレンヤンバ
10
    Elucidation of the molecular mechanism of galectin-3 in the progression of urological cancer
    • 批准号:
      18K09136
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.91万
    • 财政年份:
      2018
    • 负责人:
      FUKUMORI Tomoharu
    • 依托单位:
    Elucidation of tumor regulation mechanism of galectin-3 against castration-resistant prostate cancer and clinical application
    • 批准号:
      15K10592
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.08万
    • 财政年份:
      2015
    • 负责人:
      FUKUMORI Tomoharu
    • 依托单位:
    The tumor control mechanism of galectin-3 in prostate cancer bone metastasis
    • 批准号:
      24592394
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.33万
    • 财政年份:
      2012
    • 负责人:
      FUKUMORI Tomoharu
    • 依托单位:
    Application of galectin-3 in combined therapy of urogenital cancer
    • 批准号:
      19591854
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.0万
    • 财政年份:
      2007
    • 负责人:
      FUKUMORI Tomoharu
    • 依托单位: