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Properties of polysaccharide gel as a component of biofilms on the biomaterial surfaces related to the suppression of quorum sensing

Properties of polysaccharide gel as a component of biofilms on the biomaterial surfaces related to the suppression of quorum sensing
多糖凝胶作为生物材料表面生物膜成分与群体感应抑制相关的特性
批准号:
21592499
负责人:
NEZU Takashi
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

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中文摘要
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英文摘要
The aim of this study was to investigate the properties of hyaluronic acid gel, which is an important component of biofilms, in order to find any physicochemical conditions leading to the suppression of the quorum sensing. An antimicrobial permeated more effectively through the hyaluronic acid gel when the gel viscosity was lowered. Addition of basic(cationic) antimicrobial surfactants was especially effective to lower the gel viscosity. Those findings would lead to the tactical inhibition of infection using a disturbance of the quorum sensing by interrupting the diffusion of autoinducers through the biofilm.
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Diffusion of an antimicrobial acriflavine through a concentrated solution of hyaluronic acid as a matrix component of biofilms
抗菌吖啶黄通过作为生物膜基质成分的透明质酸浓溶液的扩散
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Nezu, T., Sasaki, K., Saitoh, S. and Taira, M.]
通讯作者: M.
酸化物材料表面への抗菌性界面活性剤の吸着と吸着層の粘弾性
抗菌表面活性剂在氧化物材料表面的吸附及吸附层的粘弹性
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [根津尚史, 他3名]
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塩基性抗菌物質の吸着を目指したアクリルレジンの調製
吸附碱性抗菌物质的丙烯酸树脂的制备
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [根津尚史, 他4名]
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Viscoelastic adlayers of collagen and lysozyme studied using quartz crystal microbalance with dissipation monitoring
使用石英晶体微天平和耗散监测研究胶原蛋白和溶菌酶的粘弹性吸附层
DOI: 10.1016/j.ijbiomac.2010.02.005
发表时间: 2010
期刊: Int J Biol Macromol
影响因子: 8.2
作者: [Nezu T, Taira M, Saitoh S, Sasaki K, Araki Y]
通讯作者: Araki Y
11
    Stable dispersion of antimicrobial surfactants to acrylic resin and its effects on the bulk and surface properties of the resin
    Quantitative analysis of swelling-shrinking nature accompanyingmolecular transfer found in natural polymers gel as potential functional biomaterials
    • 批准号:
      19592258
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.0万
    • 财政年份:
      2007
    • 负责人:
      NEZU Takashi
    • 依托单位:
    Analysis of interaction between dental structural protein and adhesive component substances by circular dichroism measurement
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