Mesenchymal stem cells-photocurable gelatin-based gelation material for application to periodontal regeneration
Mesenchymal stem cells-photocurable gelatin-based gelation material for application to periodontal regeneration
批准号:
21592501
负责人:
NAKAGAWA Taneaki
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
We confirmed that prospective isolatedMSCs showed a 120, 000-fold higher colony forming frequency thanthe conventional MSCs. Furthermore, Our results suggested that MSCs in adultbone marrow have at least two developmental origins, one of which is the neural crest. Furthermore, prospectively enrichedMSCs are a promising candidate for the efficient generation of high-quality iPS cells. This photocurable solution also has adequate viscosity at room temperature before curing, and it manipulation is enhanced. It is assumed that forms suitable for various bone defects will thus be easily rendered, and it is also assumed that the shape can be retained with the mechanical strength required by photocurable.
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Mesp1+ early paraxial mesodermal cells supply initial bone marrow mesenchymal stem cells capable of differentiating into neural crest lineage cells.
Mesp1 早期近轴中胚层细胞提供能够分化为神经嵴谱系细胞的初始骨髓间充质干细胞。
DOI:
--
发表时间:
2011
期刊:
Inflammation and Regeneration 31(1)
影响因子:
--
作者:
[Niibe K, Morikawa S, Mabuchi Y, Araki D, Nakagawa T, Okano H, Matsuzaki Y]
通讯作者:
Matsuzaki Y
DOI:
10.2492/inflammregen.30.55
发表时间:
2010-01
期刊:
Inflammation and Regeneration
影响因子:
8.1
作者:
[Lawrence Lein;Y. Nagai;Y. Mabuchi;Sadafumi Suzuki;S. Morikawa;Y. Matsuzaki]
通讯作者:
Lawrence Lein;Y. Nagai;Y. Mabuchi;Sadafumi Suzuki;S. Morikawa;Y. Matsuzaki
Flow cytometric isolation and clonal identification of mesenchymal stem cells in human bone marrow
人骨髓间充质干细胞的流式细胞术分离与克隆鉴定
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Mabuchi, Yo(発表者), Morikawa, Satoru, Suzuki, Sadafumi, Lein, Lawrence, Niibe, Kunimichi, Nagai, Yasuo, Sunabori, Takehiko, Okano, Hideyuki, Matsuzaki, Yumi, Yo Mabuchi]
通讯作者:
Yo Mabuchi
DOI:
10.1016/j.expneurol.2010.04.020
发表时间:
2010-08-01
期刊:
EXPERIMENTAL NEUROLOGY
影响因子:
5.3
作者:
[Mukaino, Masahiko, Nakamura, Masaya, Okano, Hideyuki]
通讯作者:
Okano, Hideyuki
ヒト間葉系幹細胞の予期的分離とClonal解析
人间充质干细胞的预期分离和克隆分析
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[森川暁、新部邦透, 他]
通讯作者:
他
共 9 条
Practical periodontal tissue regeneration therapy using highly purified dental pulp MSCs, induced neural crest cells, and induced odontogenic mesenchymal cells
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批准号:18K09606
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
-
财政年份:2018
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负责人:NAKAGAWA Taneaki
-
依托单位:
Elucidation of chronic periodontitis tissue destruction and tissue remodeling mechanism as seen from the periodontal tissue stem cells
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批准号:24592965
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.41万
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财政年份:2012
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负责人:NAKAGAWA Taneaki
-
依托单位:
The Effect of antimicrobial agent to artificial biofilm formed by periodontopathic bacteria
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批准号:17592164
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.01万
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财政年份:2005
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负责人:NAKAGAWA Taneaki
-
依托单位:
The analysis of the immune response to the virulence factors of the periodontopathic bacteria
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批准号:12672040
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
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财政年份:2000
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负责人:NAKAGAWA Taneaki
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依托单位:
海外基金