Chemistry of Novel Naturally Occurring Super-carbon-chain Molecules

我们将海洋生物衍生的无重复基序的长碳链分子称为超碳链分子。它们具有非凡的化学结构，并表现出强烈的生物活性。在这项研究中，我们试图通过一种新的方法来鉴定新的超碳链分子：大规模培养共生细菌或元基因组方法。我们还研究了这些分子的生物学意义、生物活性、生物合成和独特的化学反应性。结果，我们成功地鉴定了几个重要的分子，并确定了它们的生物活性。我们的发现应该有助于建立超级碳链分子的概念。

We refer to marine organism-derived long carbon chain molecules without repeating motifs as super-carbon-chain molecules. They have extraordinary chemical structures and exhibit strong biological activities. In this study, we endeavored to identify novel super-carbon-chain molecules by a new approach: the large-scale cultivation of symbiotic bacteria or a meta-genomic method. We also studied the biological significance, biological activities, biosynthesis, and unique chemical reactivities of these molecules. As a result, we successfully identified several important molecules and determined their biological activities. Our findings should help to establish the concept of super-carbon-chain molecules.