Dynamic functional analysis and construction of solid image of peripheral vessels by optical coherence tomography

本研究应用汗源光学相干断层扫描技术对皮肤表面下的外周血管进行动态观察和分析。在实验中，我们研制了一套具有5μm高分辨率和50帧/ s高图像采集速率的OCT系统。在体动态观察功能分析不仅显示了人手指的小动脉和静脉，而且还显示了微动脉和微静脉。特别地，我们通过三维OCT图像开发了小动脉和小静脉的实体图像。此外，同时测量周围血管的自主神经系统的活动的生理功能的动力学进行了演示。

In this study, it is demonstrated that dynamic observation and analysis of peripheral vessels underneath skin surface by sweat-source optical coherence tomography. In the experiment, we developed OCT system which has the high image resolution of 5μm with the high image acquisition rate of 50 frames/ s. In vivo observation for dynamic functional analysis not only small arteries and veins of human fingers but also arteriole and venule were demonstrated. In particular, we developed the solid image of the arteriole and the venule by the 3-dimensional OCT images. Furthermore, simultaneous measurement of dynamics of the physiological function of peripheral vessels for the activity of the autonomic nervous system were demonstrated.