Development of non-invasive procedures for the diagnosis of chronic hepatitis and non-alcoholic steatohepatitis(NASH) using ultrasound technologies
Development of non-invasive procedures for the diagnosis of chronic hepatitis and non-alcoholic steatohepatitis(NASH) using ultrasound technologies
批准号:
21300194
负责人:
IIJIMA Hiroko
金额:
$11.98万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
The diagnostic performance of non-contrast enhanced ultrasound and contrast enhanced ultrasound(CEUS) for chronic hepatitis and non-alcoholic steatohepatitis(NASH) were evaluated. A new diagnostic method for chronic hepatitis was developed using Virtual Touch Tissue Quantification(VTTQ). The diagnosis of NASH by CEUS using Sonazoid was studied. Observations using intravital microscopy on a rat NASH model revealed that the uptake of Sonazoid by Kupffer cells(KCs) did not increase over time, and that was considered due to the decreased phagocytic ability of KCs. The diagnosis of NASH by VTTQ at early stages of the disease suggested some issues that still need to be explored.
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Usefulness of VTTQ(Virtual Touch Tissue Quantification) to diagnose fibrosis and inflammation in chronic hepatitis
VTTQ(虚拟接触组织定量)在诊断慢性肝炎纤维化和炎症中的有用性
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Iijima H, Tanaka H, Ikeda N, Enomoto H, Iwata Y, Imanishi H, Shimomura S, Fujimoto J, Hirota S, Tsujimura T, Mogushi K, Tanaka H, Nishiguchi S.]
通讯作者:
Nishiguchi S.
Kupffer細胞の形態からみたNASH発症の要因
从库普弗细胞形态看 NASH 发生的因素
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[田中弘教, 飯島尋子, 西口修平, 和氣健二郎, 市野瀬志津子, 工藤篤, 石井昭生, 高嶋智之, 坂井良行, 會澤信弘, 山本晃久, 池田直人, 岩田恵典, 榎本平之, 齋藤正紀, 今西宏安, 下村壯治, 有井滋樹]
通讯作者:
有井滋樹
Is ARFI elastography useful for fibrosis evaluation in patients with chronic HCV hepatitis in our clinical practice A multicenter international study
在我们的临床实践中,ARFI 弹性成像对慢性 HCV 肝炎患者的纤维化评估有用吗?一项多中心国际研究
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Sporea I, Sirli R, Bota S, Tanaka H, Iijima H, Badea R. I, Lupsor M, Fierbinteanu C, Takahashi H, Piscaglia F, D Onofrio M, Popescu A, Danila M.]
通讯作者:
Danila M.
VTTQ(Virtual Touch Tissue Quantification) for evaluation of liver tumors
用于评估肝脏肿瘤的 VTTQ(虚拟接触组织定量)
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Iijima H, Tanaka H, Yoshida M, Iwai T, Takashima T, Sakai Y, Aizawa N, Iwata K, Ikeda N, Iwata Y, Enomoto H, Saito M, Imanishi H, Iimuro Y, Fujimoto J, Nishiguchi S.]
通讯作者:
Nishiguchi S.
慢性肝疾患の画像診断の進歩-超音波検査は組織診断に代わりうるか
慢性肝病影像诊断进展——超声检查能否替代组织诊断?
DOI:
--
发表时间:
2011
期刊:
日本消化器病学会誌
影响因子:
--
作者:
[田中みどり, 菅原基晃, 仁木清美, 小寺宏尚, 泉唯史, 新田尚隆, 飯島尋子, 新田尚隆, 泉唯史, 飯島尋子]
通讯作者:
飯島尋子
共 53 条
Reconstruction of past 200 years sea surface and salinity change of the western tropical Pacific using coral annual bands from Palau Islands
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批准号:20740265
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$1.74万
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财政年份:2008
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负责人:IIJIMA Hiroko
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依托单位:
Establishment of a new non-invasive and quantitative liver function assessment for Non-alcoholic steatohepatitis (NASH)
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批准号:19500428
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
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财政年份:2007
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负责人:IIJIMA Hiroko
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依托单位:
Analysis of biological malignancy in early stage HCC using low MI contrast ultrasound and angiogenesis factors.
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批准号:17500336
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2005
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负责人:IIJIMA Hiroko
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依托单位:
海外基金