Development of New Strategy for Analysis of Chromatographic Behavior on the Basis of Moment Theory

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Now, various separation media having different structural characteristics of shapes and porosities, such as silica monoliths and core-shell spherical particles, are developed for improving the separation speed and efficiency of high performance liquid chromatography, which has widely been used as one of the most powerful methods for fine separation and chemical analysis. In this study, a new strateg(theory, experimental method, and data analysis procedure) was developed for quantitatively analyzing the separation properties and mechanisms of the different packing materials in detail. The strategy can provide new information about chromatographic behavior, which cannot be derived by conventional theories and models, such as the rate theory of chromatography.