Mechanisms regulating developmental fate and sex differences of the germline in Drosophiala embryos

点击翻译按钮获取中文摘要

In this study, we have been trying to clarify the mechanisms regulating developmental fate and sex differences of the germ cells in Drosophila. What has remained a fascinating puzzle is how the germ cell decides its own sex. Here, we show that a single gene(Sxl) can initiate female sexual development in the primordial germ cells(PGCs). Our findings pave the way for future work that will help to establish the extent to which sex detemination mechanism is conserved in germ cell.