Integrated research for respective role of cancer and microenvironment towards clinical application
Integrated research for respective role of cancer and microenvironment towards clinical application
批准号:
21390360
负责人:
YAMAMOTO Hirofumi
金额:
$10.9万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
(1) We reported OSNA-based diagnosis of lymph node metastasis of colorectal cancer in 2010, and Ministry of Health, Labour and Welfare permitted its usage in diagnosis.(2) We produced the C4. 4A specific antibody that recognizes only invasive cancer cells. We also found that C4. 4A promotes EMT.(3) We found that hypoxia-induced gene JMJD1A promotes EMT in colon cancer.(4) We found that carbonate apatite containing specific siRNA showed a tumor shrinkage when it is injected into the tail vein of nude mice.(5) We found inhibition of both VEGF and Ang2 led to a tumor shrinkage in nude mice.
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DOI:
--
发表时间:
2012
期刊:
Cancer Science
影响因子:
5.7
作者:
[Oshiro, Yamamoto H et al]
通讯作者:
Yamamoto H et al
Clinical application of molecular biological testing for detecting lymph node metastasis of colorectal cancer. 8th International Symposium on Minimal Residual Cancer
分子生物学检测在结直肠癌淋巴结转移检测中的临床应用
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Matsuoka T, Yamamoto A, Hamamoto S, Sogawa E, Kageyama K, Miki Y, Yoshida A, Iguci T., Hirofumi Yamamoto]
通讯作者:
Hirofumi Yamamoto
Hypoxia-inducible adrenomedullin in colorectal cancer
结直肠癌中缺氧诱导的肾上腺髓质素
DOI:
--
发表时间:
2011
期刊:
Anticancer Res
影响因子:
2
作者:
[Uemura M, Yamamoto H et al]
通讯作者:
Yamamoto H et al
DOI:
10.1111/j.1478-3231.2011.02619.x
发表时间:
2012-01-01
期刊:
LIVER INTERNATIONAL
影响因子:
6.7
作者:
[Noda, Takehiro, Yamamoto, Hirofumi, Nagano, Hiroaki]
通讯作者:
Nagano, Hiroaki
Clinical application of molecular biological testing for detecting lymph node metastasis of colorectal cancer
分子生物学检测结直肠癌淋巴结转移的临床应用
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Hirofumi Yamamoto, et al]
通讯作者:
et al
共 11 条
Development of nucleic acid therapy using rapid acting DDS
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批准号:15H04920
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.23万
-
财政年份:2015
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负责人:YAMAMOTO Hirofumi
-
依托单位:
Study of the tsunami history that attacked the Wakasa Bay area.
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批准号:24540487
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.33万
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财政年份:2012
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负责人:YAMAMOTO Hirofumi
-
依托单位:
Identification of microRNA that correctly inhibits KRAS-related downstream signal transduction in KRAS mutant colorectal cancer
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批准号:24659608
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
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财政年份:2012
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负责人:YAMAMOTO Hirofumi
-
依托单位:
macro-cosmos in interaction between cancer and host microenvironments.
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批准号:24390315
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.81万
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财政年份:2012
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负责人:YAMAMOTO Hirofumi
-
依托单位:
The reserch of the political desidion system in Edo period
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批准号:23242037
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$9.24万
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财政年份:2011
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负责人:YAMAMOTO Hirofumi
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依托单位:
Design of solid supported carbaborane catalyst with the aim of developing latent reactivity and reuse methods
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批准号:23790034
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.75万
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财政年份:2011
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负责人:YAMAMOTO Hirofumi
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依托单位:
Paleoseismological survey of the Sabae Fault in the seismic gap around the Seibu-basin, Fukui Prefecture, central Japan.
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批准号:21540470
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2009
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负责人:YAMAMOTO Hirofumi
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依托单位:
The study of historical materials studies of annals/the editing source book of the Edo Shogunate/the Imperial Court/various feudal clans
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批准号:18202018
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$20.63万
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财政年份:2006
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负责人:YAMAMOTO Hirofumi
-
依托单位:
Development of novel therapeutic strategy based on malignant nature of colorectal cancer
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批准号:16591313
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2004
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负责人:YAMAMOTO Hirofumi
-
依托单位:
Debris avalanche deposits from Kyogatake Volcano and the recent faulting events in Fukui Prefecture, central Japan.
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批准号:16540414
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.37万
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财政年份:2004
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负责人:YAMAMOTO Hirofumi
-
依托单位:
Tectonic activity around the Fukul plane and its evaluation
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批准号:13640455
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.11万
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财政年份:2001
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负责人:YAMAMOTO Hirofumi
-
依托单位:
海外基金