课题基金 / 基金详情

Integrated research for respective role of cancer and microenvironment towards clinical application

Integrated research for respective role of cancer and microenvironment towards clinical application
癌症与微环境各自作用的综合研究及其临床应用
批准号:
21390360
负责人:
YAMAMOTO Hirofumi
金额:
$10.9万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

项目摘要

项目成果

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中文摘要
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英文摘要
(1) We reported OSNA-based diagnosis of lymph node metastasis of colorectal cancer in 2010, and Ministry of Health, Labour and Welfare permitted its usage in diagnosis.(2) We produced the C4. 4A specific antibody that recognizes only invasive cancer cells. We also found that C4. 4A promotes EMT.(3) We found that hypoxia-induced gene JMJD1A promotes EMT in colon cancer.(4) We found that carbonate apatite containing specific siRNA showed a tumor shrinkage when it is injected into the tail vein of nude mice.(5) We found inhibition of both VEGF and Ang2 led to a tumor shrinkage in nude mice.
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会议论文
DOI: --
发表时间: 2012
期刊: Cancer Science
影响因子: 5.7
作者: [Oshiro, Yamamoto H et al]
通讯作者: Yamamoto H et al
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Matsuoka T, Yamamoto A, Hamamoto S, Sogawa E, Kageyama K, Miki Y, Yoshida A, Iguci T., Hirofumi Yamamoto]
通讯作者: Hirofumi Yamamoto
Hypoxia-inducible adrenomedullin in colorectal cancer
结直肠癌中缺氧诱导的肾上腺髓质素
DOI: --
发表时间: 2011
期刊: Anticancer Res
影响因子: 2
作者: [Uemura M, Yamamoto H et al]
通讯作者: Yamamoto H et al
DOI: 10.1111/j.1478-3231.2011.02619.x
发表时间: 2012-01-01
期刊: LIVER INTERNATIONAL
影响因子: 6.7
作者: [Noda, Takehiro, Yamamoto, Hirofumi, Nagano, Hiroaki]
通讯作者: Nagano, Hiroaki
11
    Development of nucleic acid therapy using rapid acting DDS
    • 批准号:
      15H04920
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
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    macro-cosmos in interaction between cancer and host microenvironments.
    • 批准号:
      24390315
    • 项目类别:
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    • 财政年份:
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    • 负责人:
      YAMAMOTO Hirofumi
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