课题基金 / 基金详情

Prospective isolation of pancreatic cancer cells with highly malignant phenotype and development of future individualized therapy

Prospective isolation of pancreatic cancer cells with highly malignant phenotype and development of future individualized therapy
具有高度恶性表型的胰腺癌细胞的前瞻性分离和未来个体化治疗的发展
批准号:
21390381
负责人:
TANAKA Masao
金额:
$11.23万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

项目摘要

项目成果

TANAKA Masao的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
We identified CD133 positive pancreatic cancer cells with high malignant potential. CD133 positive pancreatic cancer cells have strong invasive ability via SDF1-CXCR4 pathway. We also found that migration of CD105 positive pancreatic cancer cells was promoted by cancer-stromal interactions. Moreover, we clarified that collagen-internalization receptor CD280 was an important molecule for invasion of pancreatic cancer cells. We reduced the invasion of pancreatic cancer cells by knockdown of CD280. In the present study, we identified several molecules as promising therapeutic targets.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Pancreatic Stellate Cells Promote Migration of CD105+ Pancreatic Cancer Cells
胰腺星状细胞促进 CD105 胰腺癌细胞的迁移
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Taipei, Taiwan]
通讯作者: Taiwan
膵癌におけるCD133陽性細胞は、癌間質作用を介してより高い遊走・浸潤能を獲得する
胰腺癌中的CD133阳性细胞通过癌基质作用获得更高的迁移和侵袭能力
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [森山大樹, 大内田研宙, 水元一博, 崔林, 余俊, 江上拓哉, 藤田逸人, 佐藤典宏, 当間宏樹, 永井英司, 田中雅夫]
通讯作者: 田中雅夫
The Functional Heterogeneity of Pancreatic Cancer Cells and Surrounding Stromal Cells in Cancer-Stromal Interactions
胰腺癌细胞和周围基质细胞在癌症-基质相互作用中的功能异质性
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Ohuchida K., et al]
通讯作者: et al
分子発現解析に基づく膵癌診断法とその意義 特集『膵癌に対するトランスレーショナルリサーチの展望』 膵臓
基于分子表达分析的胰腺癌诊断及其意义 专题:“胰腺癌转化研究展望” 胰腺
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [大内田研宙, 大塚隆生, 水元一博, 田中雅夫]
通讯作者: 田中雅夫
16
    A new strategy for improving the efficacy of the conventional therapy of pancreatic cancer by remodeling its microenvironment
    • 批准号:
      25670586
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.33万
    • 财政年份:
      2013
    • 负责人:
      TANAKA Masao
    • 依托单位:
    Identifying the leading cell for the invasion of pancreatic cancer
    • 批准号:
      24390318
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.65万
    • 财政年份:
      2012
    • 负责人:
      TANAKA Masao
    • 依托单位:
    Establishment of therapy for individual based on diagnostic imaging by artificial virus
    • 批准号:
      23659655
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.33万
    • 财政年份:
      2011
    • 负责人:
      TANAKA Masao
    • 依托单位:
    ANALYSES OF THE SIGNAL TRANSDUCTION OF NOVEL ANTI-ARTHRITIC FACTOR, FRP, AND ITS EFFECTS ON IMMUNE SYSTEM
    • 批准号:
      18591105
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.51万
    • 财政年份:
      2006
    • 负责人:
      TANAKA Masao
    • 依托单位:
    海外基金