Patient specific individual computational mechanics for diagnosis and treatment planning of temporomandibular joint disorder

用于颞下颌关节紊乱的诊断和治疗计划的患者特定个体计算力学

• 批准号: 14380402
• 负责人: TANAKA Masao
• 金额: $ 9.54万
• 依托单位: Osaka University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2002
• 资助国家: 日本
• 起止时间: 2002 至 2004
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-14380402/
• 关键词: Biomechanics; Computational Mechanics; Individual Modeling; Temporomandibular joint; 個体別モデリング

Individual geometry of temporomandibular joint(TMJ) was retrieved from MR images and was used for the finite element modeling of individual patient. The condyle trajectory was determined by referring to its position at different mouth opening positions, and used for the stress analysis of soft tissue components of temporomandibular joints. The typical stress conditions in the TMJ disc and the retrodiscal connective tissue were investigated for normal TMJs and for anterior-disc-displaced TMJs. The sensitivity analysis with condyle position demonstrated that the perturbation in inferior direction at the fully-mouth-open position and the perturbation in inferior direction with small rotation at the mouth-closed position were effective for the disc reduction during the mouth opening motion of anterior-disc-displaced TMJs. The individual finite element model was extended with the frame structures for the mandible bone connected to the finite elements of condyle and for the temporal bone behind the elements of glenoid fossa. These frames were interconnected by muscles of mastication under the contacting conditions at anterior/posterior tooth, and the extended model enabled us to examine the stress condition of soft tissue components of viscoelasticity under the clenching. The parameter studies suggested us that the comparison of the results of individual finite element analysis with the results of medical imaging analysis has the potential to estimate the elastic characteristics of the soft tissue components towards the diagnosis and to probe the treatment condition of the adjustment of relative position of bony components leading the condyle trajectory for the reasonable stress condition of the soft tissue components.

从MR图像中检索颞下颌关节（TMJ）的个体几何形状，并用于个体患者的有限元建模。根据不同张口位时髁突的位置确定髁突的运动轨迹，并用于颞下颌关节软组织成分的应力分析。在TMJ盘和retrodiscal结缔组织的典型应力条件进行了研究，为正常的TMJ和前盘移位的TMJ。对髁突位置的敏感性分析表明，张口位向下扰动和闭口位向下扰动加小旋转均能有效降低盘前移位颞下颌关节张口运动时的盘复位。将下颌骨的框架结构与髁突的有限元单元连接，颞骨的框架结构与关节窝的有限元单元连接，扩展了个体化有限元模型。这些框架在前/后牙接触条件下由咀嚼肌相互连接，扩展模型使我们能够检查在紧握时软组织粘弹性成分的应力状况。参数研究表明，个体有限元分析结果与医学影像分析结果的比较，有可能估计软组织成分的弹性特性，以诊断和探讨的治疗条件的相对位置的调整骨组件导致髁突轨迹的软组织成分的合理应力条件。

项目成果

顎関節の個体別計算バイオメカニクスシミュレーション

颞下颌关节的个体计算生物力学模拟

• 发表时间: 2005
• 期刊: 日本顎口腔機能学会雑誌 11-2
• 作者: Yagi N;Shimizu J;Mohri S;Araki J;Nakamura K;Okuyama H;Toyota H;Morimoto T;Morizane Y;Kurusu M;Miura T;Hashimoto K;Tsujioka K;Suga H;Kajiya F;田中 正夫
• 通讯作者: 田中 正夫

Influence of Condyle Trajectory on Biomechanical Condition of Soft Tissue Components in Anterior-Disc-Displaced Tempromandibular Joint

髁突轨迹对前盘移位颞下颌关节软组织部件生物力学状况的影响

• 发表时间: 2005
• 期刊: Computer Methods in Biomechanics & Biomedical Engineering 5
• 作者: Nakamura M;et al.;Masao Tanaka
• 通讯作者: Masao Tanaka

田中正夫: "個体別有限要素モデルによる関節円板前方転位顎関節の応力解析"日本機械学会論文集A編. 69-677. 141-147 (2003)

Masao Tanaka：“使用单个有限元模型对颞下颌关节进行前椎间盘移位的应力分析”，日本机械工程师学会汇刊，A 版 69-677（2003 年）。

黒田有紀子: "下顎頭運動軌跡が顎関節軟組織力学状態に及ぼす影響"日本機械学会講演論文集. 03-19. 63-64 (2003)

Yukiko Kuroda：“下颌髁运动轨迹对颞下颌关节软组织机械状态的影响”日本机械工程师学会会议记录 03-19（2003）。

M.TANAKA: "Influence of condyle trajectory on biomechanical condition of soft tissue components in an terior-disc-displaced temporomandibular joint : individual-model based analysis"Computer Methods in Biomechanics and Biomedical Engineering. (In press).

M.TANAKA：“髁突轨迹对前椎间盘移位颞下颌关节软组织成分生物力学状况的影响：基于个体模型的分析”生物力学和生物医学工程中的计算机方法。