Social anthropological study for genotypes of oral Candida albicans from healthy people in Central Asia

中亚健康人群口腔白色念珠菌基因型的社会人类学研究

• 批准号: 21405002
• 负责人: TANAKA Reiko
• 金额: $ 12.15万
• 依托单位: Chiba University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21405002/
• 关键词: カンジダ・アルビカンス; 民族; 常在性; 遺伝子型; 新疆ウイグル自治区; トルコ; 常在菌; カシュガル; ヒト常在菌; 中央アジア; シルクロード; 遺伝子; カンジダ; 民族移動; AIDS; 薬剤感受性

Candida albicans are known to be one of normal oral resident microorganisms. We developed some tools for discrimination of C. albicans . We aim to know the relation between race and their genotypes of C. albicans. In old literature, Japanese people were originated from Central Asia (Mongolian). The Silk Road (from the ancient the Roman Empire to Japan through Turkey and Xinjiang) is very interesting route of people moving. We surveyed their genotypes in Japan, Xinjiang (Turpan, Ili, Kashgar) and Turkey (Adana).The genotype common to all was found in comparison of the genotype for every area. Moreover, although characteristic main genotypes were found in every area, there was nothing in Kashgar. This result showed that genotypes were very various in Kashgar. In Adana (Turkey), the frequency of genotype D was very high, and the feature of this area was shown. As mentioned above, the feature peculiar to the area was able to be found out by comparison of the genotype.

白色念珠菌是口腔常见的常驻微生物之一。我们开发了一些判别C.白色念珠菌目的是了解C.白色念珠菌在古代文献中，日本人起源于中亚（蒙古）。丝绸之路（从古罗马帝国到日本，经过土耳其和新疆）是一条非常有趣的人们流动的路线。我们对日本、新疆吐鲁番、伊犁、喀什和土耳其阿达纳三个地区的基因型进行了调查，比较了各地区的基因型，发现了共同的基因型。各地区均发现有特征性的主基因型，但喀什地区无主基因型。这一结果表明喀什地区的基因型差异很大。土耳其阿达纳地区D基因型频率较高，显示了该地区的特点。如上所述，通过基因型的比较，能够发现该地区特有的特征。

项目成果

Genotyping of Fluconazole-resistant Candida albicans Isolated from Uighurian People in Xinjing (China) Using ALTS/RFLP and Micro-TGGE method

使用 ALTS/RFLP 和 Micro-TGGE 方法对中国新疆维吾尔族人群分离的耐氟康唑白色念珠菌进行基因分型

• DOI: 10.3314/jjmm.51.165
• 发表时间: 2010
• 期刊: Nippon Ishinkin Gakkai Zasshi
• 作者: Mijiti J;XM Pu;Erfan A;Yaguchi T;Chibana H;Tanaka R
• 通讯作者: Tanaka R

Genotyping of Candida albicans spp. Isolated from oral candidiasis of HIV/AIDS infected patients in Indonesia : A molecular epidemiological studies

白色念珠菌属的基因分型。

• 发表时间: 2010
• 作者: Khaedir Y;Tanaka R;Tarini A;Mijiti J;Gonoi T
• 通讯作者: Gonoi T

ヒト口腔内常在性Candida albicans のgenotype解析

人类口腔中白色念珠菌的基因型分析

• 发表时间: 2010
• 作者: 高木雄基;服部尚生;足立秀禎;田中玲子;深野英夫;神戸俊夫
• 通讯作者: 神戸俊夫

Genotyping of fluconazole-resistant Candida albicans isolated from Uighurian living in Xinjiang (China), using ALTS/RFLP and t-TGGE method

使用 ALTS/RFLP 和 t-TGGE 方法对生活在新疆（中国）的维吾尔族人中分离的耐氟康唑白色念珠菌进行基因分型

• 发表时间: 2010
• 期刊: Jpn J Med Mycol
• 作者: Mijiti J;XM Pu;A Erfan;T Yaguchi;H Chibana;R Tanaka
• 通讯作者: R Tanaka

Genetic and phenotypic heterogeneity in clinical Candida albicans isoletes from Beijing, China

中国北京临床白色念珠菌分离株的遗传和表型异质性

• 发表时间: 2011
• 作者: Li HM;Imanishi Y;Tanaka R;Li RY;Yaguchi T
• 通讯作者: Yaguchi T