In situ component selective determination of elastic modulus of bone tissue without loading.

通过测量骨胶原X射线衍射强度与温度的关系，在不加载试件的情况下，测定骨胶原的弹性模数。一般而言，骨胶原的衍射光与矿物的衍射光叠加。我们制备了含有三分之一天然骨的矿物质含量的骨标本。对于这些标本，胶原的模量值比肌腱胶原的模量值大几倍。证实了矿物质对骨胶原的强化作用，得出骨胶原的表观模量值远大于肌腱胶原的表观模量值。

Elastic modulus of collagen in bone was determined without loading to the specimen by measuring temperature dependence of X-ray diffraction intensity from collagen. In general, diffraction from collagen in bone is superimposed by that from mineral. We prepared bone specimens with mineral fraction one third of native bone. For these specimens, modulus values of collagen several times larger than that of tendon collagen were obtained. Then, reinforcement of collagen in bone by mineral was confirmed and much larger apparent modulus values for bone collagen than those of tendon collagen were deduced.