Immobilization of Biomaterials Using Chemical Modification by Plasma Treatment and Its Application for Biosensor

等离子体处理化学修饰生物材料的固定化及其在生物传感器中的应用

• 批准号: 21740395
• 负责人: OGINO Akihisa
• 金额: $ 2.91万
• 依托单位: Shizuoka University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21740395/
• 关键词: プラズマ; 表面・界面物性; ナノバイオ; 化学修飾; アミノ基; 生態材料; 多糖類

To develop biosensors, the effect of plasma treatment on the immobilization of biomaterials was studied. To immobilize the biomaterials, the functional groups such as amino and hydroxyl groups that act as the linker are introduced by plasma treatment. In the experiment, the ammonia or water vapor was used as plasma gas to introduce amino or hydroxyl groups, respectively. The experimental results show that the plasma treatment is effective for selective immobilization on the surface and the introduced functional groups contribute the immobilization of biomaterials.

为了研制生物传感器，研究了等离子体处理对生物材料固定化的影响。为了使生物材料稳定，通过等离子体处理引入用作连接体的官能团，例如氨基和羟基。在实验中，氨或水蒸气被用作等离子体气体，分别引入氨基或羟基。实验结果表明，等离子体处理是有效的选择性固定在表面上，引入的功能基团有助于生物材料的固定。