Establishment of new lipidomics approach

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We successfully established the new lipidomics approach named "TLC-Blot-MALDI imaging" which visualizes the lipid pattern obtained from thin layer chromatography by imaging mass spectrometry which is new analytical skills.In this study, we evaluated the validity of the technique, and also applied to the biological samples. As a result, we succeeded to detect very small amounts of lipids which hardly detected by conventional methods. Moreover, comprehensive analyses were also performed to know the lipid dynamics change with molecular species level.