Development of new therapy for spinal cord injury in dogs using locomotor training
Development of new therapy for spinal cord injury in dogs using locomotor training
批准号:
21780284
负责人:
KAMISHINA Hiroaki
金额:
$2.83万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
本研究以脊髓损伤大鼠模型和犬临床病例为研究对象,探讨运动训练治疗脊髓损伤的新方法。与对照组和常规推车组相比,用LT推车训练的瘫痪大鼠后肢功能得到改善。瘫痪犬在地面上进行肝移植术后有所改善,但使用肝移植术推车的效果未得到证实。LT车的进一步修改正在进行中。
英文摘要
This research was conducted to develop new therapy for spinal cord injury(SCI) by locomotor training(LT), using a rat model and canine clinical cases of SCI. Paralysed rats trained with a LT cart improved hindlimb function compared with contorl and conventional cart groups. Paralysed dogs improved with over-ground LT, but the efficacy was not confirmed with a LT cart. Further modification of the LT cart is underway.
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DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[神志那弘明]
通讯作者:
神志那弘明
Study on pathomechanisms of canine degenerative myelopathy and preclinical trial for antibody therapy
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批准号:24380169
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.32万
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财政年份:2012
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负责人:KAMISHINA Hiroaki
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依托单位:
海外基金