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Role of the interaction of extracellular matrix with integrin in the cardiovascular disease

Role of the interaction of extracellular matrix with integrin in the cardiovascular disease
细胞外基质与整合素相互作用在心血管疾病中的作用
批准号:
21790696
负责人:
MATSUI Yutaka
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010

项目摘要

项目成果

MATSUI Yutaka的其他基金

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中文摘要
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英文摘要
The interactions between extracellular matrix proteins and integrins play pivotal roles in the development of many cardiovascular diseases, including cardiac remodeling after myocardial infarction (MI) and atherosclerosis. We had two major novel findings as below. 1) Syndecan-4 and alpha9 integrin plays a critical role in the cardiac healing process after MI. 2) Syndecan-4 deficiency limits neointimal formation after vascular injury by regulating vascular smooth muscle cell proliferation and vascular progenitor cell mobilization.
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会议论文
The role of osteopontin in the cardiovascular diseases
骨桥蛋白在心血管疾病中的作用
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [松井裕, et al.]
通讯作者: et al.
Blockade of interaction of alpha9 integrin with its ligands hinders the formation of granulation in cutaneous wound healing
阻断α9整合素与其配体的相互作用阻碍皮肤伤口愈合中肉芽的形成
DOI: --
发表时间: 2010
期刊: Lab invest
影响因子: 5
作者: [Nakayama Y, Kon S, Kurotaki D, Morimoto J, . Matsui Y, and Uede T]
通讯作者: and Uede T
DOI: 10.1002/art.24705
发表时间: 2009-08-01
期刊: ARTHRITIS AND RHEUMATISM
影响因子: --
作者: [Matsui, Yuichiro, Iwasaki, Norimasa, Uede, Toshimitsu]
通讯作者: Uede, Toshimitsu
Alpha9 integrin and its ligands constitute critical joint microenvironments for development of autoimmune arthritis.
Alpha9 整合素及其配体构成了自身免疫性关节炎发展的关键关节微环境。
DOI: --
发表时间: 2009
期刊: J Immunol. 182
影响因子: --
作者: [Kanayama, M., Matsui, Y., et al]
通讯作者: et al
12
    Microlocal analysis of topological Radon transforms and their applications to singularity theory
    • 批准号:
      15K17564
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $1.66万
    • 财政年份:
      2015
    • 负责人:
      MATSUI Yutaka
    • 依托单位:
    Microlocal analysis of topological Radon transforms and their application to singularity thoery
    • 批准号:
      23740134
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $1.5万
    • 财政年份:
      2011
    • 负责人:
      MATSUI Yutaka
    • 依托单位:
    Microlocal analysis of constructible functions and their applications to singularity theory
    • 批准号:
      20840040
    • 项目类别:
      Grant-in-Aid for Young Scientists (Start-up)
    • 资助金额:
      $1.68万
    • 财政年份:
      2008
    • 负责人:
      MATSUI Yutaka
    • 依托单位:
    Role of the interaction of extracellular matrix with integrin in the cardiovascular disease
    • 批准号:
      19790508
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.42万
    • 财政年份:
      2007
    • 负责人:
      MATSUI Yutaka
    • 依托单位: