The investigation of the cause of type 1 diabetes and the development of its prediction system.

目前对1型糖尿病的干预是困难的，也是不够成功的，因此，根除1型糖尿病的唯一途径是预测并相应地预防该疾病。本研究的目的是发现1型糖尿病的遗传决定因素，并开发1型糖尿病的预测系统。在这项研究中，我成功地建立了新的胰岛素自身抗体检测方法。此外，我还开发了一个用于1型糖尿病早期诊断的筛查小组。

The intervention of type 1 diabetes is difficult and not enough successfully at the moment, and therefore the only way for the eradication of type 1 diabetes is prediction, and consequent prevention of the disease. The aim of this study is to discover genetic determinants of type 1 diabetes, and to develop a prediction system for type 1 diabetes. In this study, I succeeded in the construction of new assay for insulin autoantibody. In addition, I developed a screening panel for early diagnosis of type 1 diabetes.