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Identification of molecular basis of acute-and lymphoma-type adult T-cell leukemia/lymphoma

Identification of molecular basis of acute-and lymphoma-type adult T-cell leukemia/lymphoma
急性和淋巴瘤型成人 T 细胞白血病/淋巴瘤的分子基础鉴定
批准号:
21790930
负责人:
NAKAGAWA Masao
金额:
$2.75万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010

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中文摘要
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英文摘要
Acute-type adult T-cell leukemia/lymphoma (ATLL) cases frequently have lymph node lesions. I performed detailed genomic analysis and clarified; 1) a part of such cases had genomic alterations similar to those frequently found in lymphoma-type ATLL, 2) multiple subclones with various additional genomic alterations were frequently found in a lymph node of individual cases and a selected subclone among the lymph node subclones appeared in peripheral blood. These new findings indicate that a part of acute-type ATLL cases should be categorized as lymphoma-type ATLL with leukemic change.
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DOI: 10.1182/blood-2008-12-194852
发表时间: 2009-09-17
期刊: BLOOD
影响因子: 20.3
作者: [Honma, Keiichiro, Tsuzuki, Shinobu, Seto, Masao]
通讯作者: Seto, Masao
IL-4/CD40L Co-Stimulation Induces Long-Term Proliferation for CD10-Positive Germinal Center B Cell-Like Diffuse Large B-Cell Lymphoma.
IL-4/CD40L 共同刺激可诱导 CD10 阳性生发中心 B 细胞样弥漫性大 B 细胞淋巴瘤的长期增殖。
DOI: --
发表时间: 2010
期刊: The Open Leukemia Journal 3
影响因子: --
作者: [Kato, H., Kagami, Y., Nakagawa, M., et al., (他5名、3番目)]
通讯作者: (他5名、3番目)
Clonal evolution of adult T-cell leukemia/lymphoma takes place in lymph node
成人T细胞白血病/淋巴瘤的克隆进化发生在淋巴结中
DOI: --
发表时间: 2011
期刊: Blood
影响因子: 20.3
作者: [Umino A, Nakagawa M, Seto M.]
通讯作者: Seto M.
アレイCGH法を用いて明らかになった急性型成人T細胞性白血病リンパ腫と末梢T細胞性リンパ腫の類似性
使用阵列 CGH 方法揭示急性成人 T 细胞白血病淋巴瘤与外周 T 细胞淋巴瘤之间的相似性
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Honma, K., Tsuzuki, S., Nakagawa, M., et al., (他4名、3番目), Keiichiro Honma, 中川雅夫, 海野啓]
通讯作者: 海野啓
7
    Developmental analyses of the cardiac conduction system and cardiomyocytic functions in the rats with congenital cardiac anomalies
    • 批准号:
      21591386
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.91万
    • 财政年份:
      2009
    • 负责人:
      NAKAGAWA Masao
    • 依托单位:
    Developmental analysis of the proximal portion and orifices of the coronary arteries and the role of extracardiac cells in their morphogenesis
    • 批准号:
      19591203
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.83万
    • 财政年份:
      2007
    • 负责人:
      NAKAGAWA Masao
    • 依托单位:
    Array CGH analytics and gene expression analytics revealed distinct subgroups in Peripheral T cell lymphomas
    • 批准号:
      19790678
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.28万
    • 财政年份:
      2007
    • 负责人:
      NAKAGAWA Masao
    • 依托单位:
    Research on Visible Light Communication
    • 批准号:
      17206041
    • 项目类别:
      Grant-in-Aid for Scientific Research (A)
    • 资助金额:
      $30.45万
    • 财政年份:
      2005
    • 负责人:
      NAKAGAWA Masao
    • 依托单位:
    海外基金