Developmental roles of the subventricular zone-specific gene in the mammalian brain.

点击翻译按钮获取中文摘要

Mammalian cerebral cortex consists of six layers. Neurons in each layer communicate with each other and develop the complex networks. Highly sophisticated neuronal networks are considered to be origins of higher-order brain function in humans. Mammalian subventricular zone (SVZ) includes progenitor cells which generate massive amount of neurons during the brain development. In this study, we examined the expression level of SVZ-specific gene in human and mouse brain and proposed the microRNA-mediated regulatory mechanism of SVZ-specific gene expression.