Development of the periodontal reproduction type titanium implant by the surface control

移植物的表面特性影响细胞在体外的分化。细胞粘附的发生早于机器抛光表面，其修饰的纳米表面决定了我们使用线放电法影响成骨细胞和骨髓间充质系统细胞的分化。同时，我们用分化指导培养基培养成骨样细胞，并检测EDSurface对细胞分化的影响。此外，接触成骨，种植体表面引起骨形成的预期在体内。

The surface property of the implant influenced the differentiation of cells in vitro. Cell adhesion occurred earlier than machine polished surface, and the nanosurface which it modified determined that we influenced the differentiation of osteoblasts and marrow mesenchyma system cells using wire electric discharge method. Also, we cultured osteoblasts-like cells with differentiation instruction culture media and were able to examine effect to give cell differentiation of EDSurface. Furthermore, Contact osteogenesis where the implant surface caused bone formation was expected in vivo.