Exploring molecular entities of innate immune system that changes through metamorphosis in starfish

点击翻译按钮获取中文摘要

In invertebrate, a comparative analysis of larval and adult innate immune system, from a perspective of ontology, has not been made. We revealed that the allorecognition capability of immune cells is acquired after metamorphosis in the immune system of the starfish, Asterina pectinifera. Although a global analysis comparing genes expression in the larval and the adult immune cells showed that the majority of immune-related gene is common to both cell types, a certain type of gene that suggests the alteration of immune recognition system was present in these common genes.