Neural circuit mechanisms of the processing of numbers and sequences

处理数字和序列的神经回路机制

• 批准号: 21700366
• 负责人: MORITA Kenji
• 金额: $ 2.41万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21700366/
• 关键词: 計算論的神経科学; 数; 段階性; 動作制御; 大脳皮質; 神経機構; 数理モデル; 数の認識; 脳機構

I have studied neural circuit mechanisms of the processing of numbers such as the numerosity of sensory stimuli and the planning/execution of sequential actions through computational modeling, and have proposed specific models on the possibility that detailed properties of individual cortical pyramidal neurons, in particular, nonlinear input integration and cooperative plasticity induction on the dendritic branches, as well as short-term synaptic plasticity, significantly contribute to the processing of numbers and the planning/execution of sequential actions.

我通过计算模型研究了数字加工的神经回路机制，如感觉刺激的数量和序列动作的计划/执行，并提出了具体的模型，说明单个皮质锥体神经元的详细特性，特别是树突分支上的非线性输入整合和合作可塑性诱导，以及短期突触可塑性，对数字加工和序列动作的计划/执行有显著贡献。

项目成果

Dendritic Contribution to the Weber's Law in the Number Sense

数意义上的树突对韦伯定律的贡献

• 发表时间: 2009
• 作者: 仲・金田勇人;島崎琢也;岡野栄之;森田賢治
• 通讯作者: 森田賢治

Frequency preference of a layer V pyramidal neuron in response to osci llatory inhibition at the apical tuft dendrites

V 层锥体神经元响应顶端簇树突振荡抑制的频率偏好

• 发表时间: 2010
• 作者: Xiumin Li;Kenji Morita;Hugh P.C.Robinson;Michael Small
• 通讯作者: Michael Small

Spatial noise and cortical functions : Effects of the spatial variability of the inputs and the membrane properties over the dendritic tree

空间噪声和皮质功能：输入的空间变异性和树突树上的膜特性的影响

• 发表时间: 2009
• 作者: 吉原誠一;西村信城;高橋弘雄;森憲作;坪井昭夫;森田賢治
• 通讯作者: 森田賢治

Highly Differentiated Projection-Specific Cortical Subnetworks

• DOI: 10.1523/jneurosci.0772-11.2011
• 发表时间: 2011-07-13
• 期刊: JOURNAL OF NEUROSCIENCE
• 影响因子: 5.3
• 作者: Morishima, Mieko;Morita, Kenji;Kawaguchi, Yasuo
• 通讯作者: Kawaguchi, Yasuo

Spatial Noise and Cortical Functions : Potential Functional Roles of the Inhomogeneity across Dendritic Branches of Cortical Pyramidal Cells

空间噪声和皮质功能：皮质锥体细胞树突分支的不均匀性的潜在功能作用

• 发表时间: 2010
• 作者: Eiraku M;Takata N;Ishibashi H;Kawada M;Sakakura E;Okuda S;Sekiguchi K;Adachi A;Sasai Y.;森田賢治
• 通讯作者: 森田賢治