Investigation of cortical microcircuit upon meynert nucleus-induced cortical plasticity
Investigation of cortical microcircuit upon meynert nucleus-induced cortical plasticity
批准号:
21700374
负责人:
TAKATA Norio
金额:
$2.83万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010
中文摘要
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英文摘要
Two-dimensional imaging analysis was performed on calcium (Ca^<2+>) dynamics of cortical cells during long term potentiation (LTP) induced by combined stimulation to meynert nucleus (NBM) and whiskers of an anesthetized mouse. We found that cortical glial cells respond with Ca^<2+> surges during the LTP-induction. Moreover, depleting this Ca^<2+> activity led to loss of LTP while maintaining neuronal response to NBM stimulation intact. These results show for the first time in in vivo preparation that glial Ca^<2+> activity is indispensable for cortical LTP induction.
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前脳基底部コリン作動性神経核は大脳皮質アストロサイトを活性化する
基底前脑胆碱能核激活大脑皮质星形胶质细胞
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[高田則雄, 平瀬肇]
通讯作者:
平瀬肇
DOI:
10.1371/journal.pone.0020108
发表时间:
2011
期刊:
PloS one
影响因子:
3.7
作者:
[Kaneko M, Yamaguchi K, Eiraku M, Sato M, Takata N, Kiyohara Y, Mishina M, Hirase H, Hashikawa T, Kengaku M]
通讯作者:
Kengaku M
Astrocytic contribution of a sensory induced synaptic plasticity in the somatosensory cortex
体感皮层感觉诱导突触可塑性的星形胶质细胞贡献
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Norio TAKATA, Tsuneko MISHIMA, Chihiro HISATSUNE, Etsuko EBISUI, Katsuhiko MIKOSHIBA, Hajime HIRASE.]
通讯作者:
Hajime HIRASE.
The first evidence of astrocytic contribution to a sensory induced synaptic plasticity in the somatosensory cortex
星形胶质细胞对体感皮层感觉诱导突触可塑性贡献的第一个证据
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Norio TAKATA, Tsuneko MISHIMA, Chihiro HISATSUNE, Etsuko EBISUI, Katsuhiko MIKOSHIBA, Hajime HIRASE.]
通讯作者:
Hajime HIRASE.
The first evidence of astrocytic contribution to a sensory induced synaptic plasticity in the somatosensory cortex in vivo
星形胶质细胞对体内体感皮层感觉诱导突触可塑性的贡献的第一个证据
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Shimoda K, Chao ZC, Nagasaka Y, Fujii N., 高田則雄]
通讯作者:
高田則雄
Causal role of novel oscillatory activity in the thalamic reticular nucleus in fluctuating neural responses to sensory stimulation.
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批准号:19K06944
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.75万
-
财政年份:2019
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负责人:TAKATA Norio
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依托单位:
Estimation of neural activity propagation pathway in the brain by applying deep learning
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批准号:15KT0111
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.16万
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财政年份:2015
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负责人:TAKATA Norio
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依托单位:
Investigation of astrocytic involvement in the cortical plasiticity in vivo
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批准号:23700399
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.83万
-
财政年份:2011
-
负责人:TAKATA Norio
-
依托单位:
Investigation on the effects of Basal Forebrain Nuclei on the cortical micro circuit in relation with sleep and awake regulation
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批准号:19700306
-
项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.4万
-
财政年份:2007
-
负责人:TAKATA Norio
-
依托单位:
海外基金