The combination therapy of mild-hyperthermia with therapeutic ultrasound and dendritic cell-based immunotherapy
The combination therapy of mild-hyperthermia with therapeutic ultrasound and dendritic cell-based immunotherapy
批准号:
21700511
负责人:
SUZUKI Ryo
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010
中文摘要
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英文摘要
Ultrasound (US) exposure to tumor tissue which was intratumorally injected nanobubbles (Bubble liposomes(BLs)), could induce anti-tumor effect by heating and shock waves derived from disruption of BLs. In addition, we found that strong tumor-specific immunity was induced by intratumoral injection of dendritic cells (DCs) after US therapy with BLs. The combination of US therapy with nanobubbles and DC-based immunotherapy efficiently suppressed tumor growth. Therefore, this might be a useful strategy for cancer therapy.
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超音波感受性リポソームを利用した新たな薬物・遺伝子送達システムの開発に関する研究
利用超声敏感脂质体开发新型药物/基因递送系统的研究
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Kumazawa, Takao, 秋吉一成, Yoshiyuki Sankai, 鈴木亮]
通讯作者:
鈴木亮
超音波感受性リポソームを利用したがん温熱療法と免疫療法の併用によるがん治療
癌症热疗和超声敏感脂质体免疫疗法相结合的癌症治疗
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[鈴木亮, 宇都口直樹, 丸山一雄]
通讯作者:
丸山一雄
DOI:
10.1089/hum.2009.106
发表时间:
2010-01-01
期刊:
HUMAN GENE THERAPY
影响因子:
4.2
作者:
[Un, Keita, Kawakami, Shigeru, Hashida, Mitsuru]
通讯作者:
Hashida, Mitsuru
Development of novel antigen delivery system with liposomal bubbles (Bubble liposomes) and ultrasound in cancer immunotherapy
开发新型脂质体气泡(气泡脂质体)和超声波抗原递送系统在癌症免疫治疗中的应用
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Ryo Suzuki, Yusuke Oda, Naoki Utoguchi, Kazuo Maruyama]
通讯作者:
Kazuo Maruyama
リポソーム型微小気泡(バブルリポソーム)を利用した超音波遺伝子・薬物デリバリー
使用脂质体型微泡(气泡脂质体)进行超声波基因/药物递送
DOI:
--
发表时间:
2009
期刊:
マテリアルインテグレーション 22(6)
影响因子:
--
作者:
[鈴木亮, 小田雄介, 宇都口直樹, 丸山一雄]
通讯作者:
丸山一雄
共 19 条
Development of regenerative medicine for refractory skin ulcers using fibroblasts
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批准号:16K10661
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Diversity-stability relationship in a plant community under climate warming
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批准号:15K07213
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.33万
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负责人:SUZUKI Ryo
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A comperative study of Japan and Canada about deinstitutionalization process and community based support system for people with intellectual disabilities
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批准号:26780329
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.5万
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Massively-Parallel Sequencing reveals molecular mechanism of gastric carcinogenesis after helicobactor pylori eradication
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批准号:25860548
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.66万
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财政年份:2013
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Mechanisms of lipid metabolism disorder in diabetic brain
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批准号:23689047
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项目类别:Grant-in-Aid for Young Scientists (A)
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资助金额:$16.22万
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负责人:SUZUKI Ryo
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依托单位:
Development of drug and gene delivery into brain with ultrasound technologies
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批准号:23500567
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.33万
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财政年份:2011
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负责人:SUZUKI Ryo
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依托单位:
change in diversity-productivity relationship along vegetative succession
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.5万
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Molecular pathogenesis of aortic dissection
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Local Historic Research on the Social Status, the Marginal Status and Buraku Problem
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批准号:21320129
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资助金额:$11.4万
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依托单位:
cancer gene therapy using non-invasive gene delivery with Bubble liposomes and ultrasound
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财政年份:2007
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Spatial and seasonal variation in competitive and facilitative effects of unpalatable plants on small palatable plants in a grazed habitat, Nara Park.
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依托单位:
Intraocular pressure and glaucoma at working places-combined study of visual function, lifestyle and a pharmacological trial
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资助金额:$9.34万
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依托单位:
Dynamics of MAP kinase cascade in immune response
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批准号:14572036
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Postive Research on Materials on Historical of Buraku Problem, "Suiheisha(The Levelers Association)
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依托单位:
Experimental Study of ZAPRINAST on Aqueous Outflow Mechanism
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批准号:10671645
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财政年份:1998
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负责人:SUZUKI Ryo
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依托单位:
Experimental Study on Aqueous Outflow of the Animal Eyes relating Insults and Intraocular Surgery
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批准号:08672018
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.09万
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财政年份:1996
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依托单位:
Studies on Liberalism in Modern Kyoto
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批准号:07451079
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项目类别:Grant-in-Aid for Scientific Research (B)
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财政年份:1995
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负责人:SUZUKI Ryo
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依托单位:
Outflow facility : conventional and unconventional flow
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批准号:04671076
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资助金额:$1.28万
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财政年份:1992
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The movement and thought of British radicalism
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批准号:02630008
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资助金额:$0.9万
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财政年份:1990
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负责人:SUZUKI Ryo
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Production of pure line in fish.
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批准号:02454080
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依托单位:
海外基金