A relationship between an enhanced sensitivity of cutaneous vasodilation response to an increase in esophageal temperature and a component synchronizing with cardiac cycle in skin sympathetic nerve activity after heat acclimation in humans.

人类热适应后皮肤血管舒张反应对食道温度升高的敏感性增强与皮肤交感神经活动中与心动周期同步的成分之间的关​​系。

• 批准号: 21700653
• 负责人: KAMIJO Yoshi-Ichiro
• 金额: $ 2.91万
• 依托单位: Shinshu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21700653/
• 关键词: 圧反射性皮膚血管拡張; 皮膚交感神経活動; 皮膚血流量; 血液量; 心周期; 暑熱トレーニング

It is well known that plasma volume (PV) expansion induced by heat acclimation enhances cutaneous vasodilation in hyperthermic humans. On the other hand, we have found that there was a component synchronizing with cardiac cycle in 1.1-1.3s latency after a given R-wave, which increased with the increase in esophageal temperature, and the increase was significantly suppressed by hypovolemia. In the present study, we have proved that an increase in the synchronizing component in hyperthermia was enhanced by PV expansion with heat acclimation, and the enhancement might be associated with an enhancement of cutaneous vasodilation in hyperthermia after heat acclimation.

众所周知，热适应诱导的血浆容量（PV）扩张增强了体温过高的人的皮肤血管舒张。另一方面，我们发现在给定的R波后1.1-1.3s潜伏期内有一个与心动周期同步的成分，它随食管温度的升高而增加，而低血容量则显著抑制了这种增加。在本研究中，我们已经证明，在高温的同步成分的增加，增强了PV扩张与热适应，增强可能与增强皮肤血管舒张热适应后的高温。

项目成果

Rapid plasma volume restoration enhances skin vasodilation but not sweat rate in hypovolemic and passively warmed men

快速血浆容量恢复可增强低血容量和被动保暖男性的皮肤血管舒张，但不会增强出汗率

• 发表时间: 2009
• 作者: Kamijo YI;Okazaki K;Ikegawa S;Okada Y;Nose H
• 通讯作者: Nose H

Pressor responses to isometric biting are evoked by somatosensory receptors in periodontal tissue in humans

• DOI: 10.1152/japplphysiol.91199.2008
• 发表时间: 2009-08-01
• 期刊: JOURNAL OF APPLIED PHYSIOLOGY
• 影响因子: 3.3
• 作者: Okada, Yoshiyuki;Kamijo, Yoshi-ichiro;Nose, Hiroshi
• 通讯作者: Nose, Hiroshi

Enhanced skin blood flow response to hyperthermia after endurance training is mainly caused by plasma volume expansion in humans.

耐力训练后皮肤血流对高温的反应增强主要是由人体血浆容量扩张引起的。

• 发表时间: 2009
• 作者: Ikegawa S;Kamijo Y;Okazaki K;Masuki S;Okada Y;Nose H.
• 通讯作者: Nose H.

Reduced hyperthermia-induced cutaneous vasodilation and enhanced exercise-induced plasma water loss at simulated high altitude (3,200 m) in humans.

在模拟高海拔 (3,200 m) 下，减少高热引起的皮肤血管舒张，增强运动引起的血浆失水。

• 发表时间: 2011
• 期刊: J Appl Physiol 110
• 作者: Miyagawa K;Kamijo Y;Ikegawa S;Goto M;Nose H.
• 通讯作者: Nose H.

Sympathetic vasoconstrictor responsiveness is reduced by 5-day endurance training with enhanced baroreflex sensitivity in men.

男性进行 5 天的耐力训练可降低交感血管收缩反应，同时增强压力反射敏感性。

• 发表时间: 2009
• 作者: Okazaki K;Kamijo Y;Masuki S;Ikegawa S;Okada Y;Yazawa D;Hata T;Shiba;Y;Takahashi M;Ikeda U;Nose H.
• 通讯作者: Nose H.