Studies on the effects of the three major nutrients on iron absorption and utilization under iron deficiency

缺铁性贫血是营养不良最严重的形式之一。营养上消除缺铁是一个主要问题。本研究的目的是研究整体饮食中铁缺乏的对应情况，而不是探索对铁缺乏有效的铁制剂。本研究旨在探讨三种主要营养素在铁缺乏情况下对铁生物利用度的改善作用，考察低聚糖在铁摄入量低和妊娠铁需求增加的情况下是否有助于铁缺乏。由此可见，添加酸性低聚木糖能保持低铁雌性成年大鼠肝脏铁的储存，促进妊娠期雌性大鼠对铁的吸收。上述结果提示，酸性低聚木糖可通过促进膳食铁的吸收和/或提高铁的生物利用度来预防缺铁性贫血。

Iron deficiency anemia is one of the most serious forms of malnutrition. Elimination of iron deficiency on nutrition is a major issue. The aim of this study was to investigate the corresponding to iron deficiency as a whole diet, instead of exploring the iron preparation in effect for iron deficiency. In this study period, to investigate the improvement of iron bioavailability by the three major nutrients under iron deficiency, it examined whether or not the oligosaccharide was useful for iron deficiency in cases of low iron intake and pregnancy increased iron demand. It demonstrated that acidic xylooligosaccharide added diet could preserve storage of hepatic iron in adult female rats fed a low iron diet and promote of dietary iron absorption in pregnancy female rats. These results suggested that acidic xylooligosaccharide could prevent iron deficiency anemia by promotion of dietary iron absorption, and/or improvement of iron bioavailability.