Studies on the effects of the three major nutrients on iron absorption and utilization under iron deficiency

缺铁性贫血是最严重的营养不良形式之一。消除缺铁对营养的影响是一大问题。本研究的目的是从整体上考察与缺铁相对应的饮食，而不是探讨铁制剂对缺铁的治疗效果。在本研究期间，为了研究缺铁情况下三种主要营养素对铁的生物利用度的改善情况，研究了在铁摄入量低和妊娠铁需求增加的情况下，低聚糖对铁缺乏症是否有用。说明添加酸性低聚木糖的饲料能保存低铁饲料饲养的成年雌性大鼠肝脏铁的储存，促进妊娠雌性大鼠膳食中铁的吸收。这些结果表明，酸性低聚木糖可通过促进膳食铁的吸收和/或提高铁的生物利用率来预防缺铁性贫血。

Iron deficiency anemia is one of the most serious forms of malnutrition. Elimination of iron deficiency on nutrition is a major issue. The aim of this study was to investigate the corresponding to iron deficiency as a whole diet, instead of exploring the iron preparation in effect for iron deficiency. In this study period, to investigate the improvement of iron bioavailability by the three major nutrients under iron deficiency, it examined whether or not the oligosaccharide was useful for iron deficiency in cases of low iron intake and pregnancy increased iron demand. It demonstrated that acidic xylooligosaccharide added diet could preserve storage of hepatic iron in adult female rats fed a low iron diet and promote of dietary iron absorption in pregnancy female rats. These results suggested that acidic xylooligosaccharide could prevent iron deficiency anemia by promotion of dietary iron absorption, and/or improvement of iron bioavailability.