Elucidation of nuclear export machinery of tRNA by crystal structural analysis of exportin/tRNA complex
Elucidation of nuclear export machinery of tRNA by crystal structural analysis of exportin/tRNA complex
批准号:
22370041
负责人:
YAMASHITA Eiki
金额:
$11.81万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
点击翻译按钮获取中文摘要
英文摘要
In eukaryotic cells, the nucleus, where transcription occurs, and thecytoplasm, where translation takes place, are separated by the nuclear envelope. Theregulation of nucleo-cytoplasmic transport of proteins and RNAs is essential for biologicalactivity. Here, we solve crystal structures of a nuclear export factor and export factorcomplex for non-coding RNA export from the nucleus and the crystal structures reveal RNArecognition mechanism of the nuclear export factor transporting various non cordingRNAs.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
DOI:
10.1093/jb/mvs085
发表时间:
2012-11
期刊:
Journal of biochemistry
影响因子:
2.7
作者:
[K. Takeshita;T. Tezuka;Y. Isozaki;E. Yamashita;Mamoru Suzuki;Minsoo Kim;Y. Yamanashi;Tadashi Yamamoto-Tad]
通讯作者:
K. Takeshita;T. Tezuka;Y. Isozaki;E. Yamashita;Mamoru Suzuki;Minsoo Kim;Y. Yamanashi;Tadashi Yamamoto-Tad
DOI:
10.1073/pnas.1019629108
发表时间:
2011-05-31
期刊:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
影响因子:
11.1
作者:
[Takeshita, Kohei, Suetake, Isao, Tajima, Shoji]
通讯作者:
Tajima, Shoji
Cramer W. A., Quinone-dependent proton transfer pathways in the photosynthetic cytochrome b6f complex.
Cramer W.A.,光合细胞色素 b6f 复合物中醌依赖性质子转移途径。
DOI:
--
发表时间:
2013
期刊:
Proc Natl Acad Sci USA
影响因子:
--
作者:
[Miya, M., Satoh, T.P., Sado, T. & Nishida, M., HasanS.S.,YamashitaE.,BaniulisD.,CramerW.A.]
通讯作者:
HasanS.S.,YamashitaE.,BaniulisD.,CramerW.A.
Crystallization and preliminary X-ray crystallographic study of the human MST2 SARAH domain.
人类 MST2 SARAH 结构域的结晶和初步 X 射线晶体学研究。
DOI:
--
发表时间:
2011
期刊:
Acta Cryst.
影响因子:
--
作者:
[Hirose T, Maita N, Taniguchi H, Sharpless KB, Omura S, Sunazuka T, ZakharovS.D.,SharmaO.,ZhalninaM.V.,YamashitaE.,CramerW.A., 宮 正樹・西田 睦, Takesita K, SongJ.,HongH.,ChoiS.,LeeY.H.,YamashitaE.,BaeS.C.,ParkI.Y.,LeeS.J.]
通讯作者:
SongJ.,HongH.,ChoiS.,LeeY.H.,YamashitaE.,BaeS.C.,ParkI.Y.,LeeS.J.
Exportin-5 によるRNAsの核外輸送メカニズムの解明
通过exportin-5阐明RNA的核输出机制
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[山澤龍治, 山下栄樹]
通讯作者:
山下栄樹
共 24 条
海外基金