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Biomarker searches and clinical applications of gastrointestinal and hepatobiliary cancers by multidisciplinary approaches

Biomarker searches and clinical applications of gastrointestinal and hepatobiliary cancers by multidisciplinary approaches
多学科方法对胃肠道和肝胆癌的生物标志物搜索和临床应用
批准号:
22390114
负责人:
NOMURA Fumio
金额:
$11.65万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

项目摘要

项目成果

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相关文献

中文摘要
翻译
通过血清深层蛋白质组分析确定了过量饮酒的新生物标志物。除了表达蛋白质组学,我们还探索了针对癌组织中过表达蛋白的抗体。血清抗ku86被认为是肝细胞癌的潜在早期诊断指标。牙龈沟液(GCF)作为近端液体的典型样本进行分析,以寻找牙周病的生物标志物。
英文摘要
Novel biomarker for excessive drinking was determined by serum deep proteome analyses. In addition to expression proteomics, antibody against proteins overexpressed in cancer tissues were explored. Serum anti-Ku86 was found to be a potential early diagnostic marker for hepatocellular carcinoma. Gingival crevicular fluid (GCF) was analyzed as a typical example of proximal fluids to search for biomarkers of periodontal diseases.
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会议论文
DOI: 10.1155/2012/623190
发表时间: 2012
期刊: International journal of proteomics
影响因子: --
作者: [Kimura A, Sogawa K, Satoh M, Kodera Y, Yokosuka O, Tomonaga T, Nomura F]
通讯作者: Nomura F
歯肉溝滲出液のプロテオーム解析による歯周疾患マーカーの探索
通过龈沟液蛋白质组分析寻找牙周病标志物
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [土田祥央, 佐藤守, 曽川一幸, 川島祐介, 荷堂清香, 澤井摂, 西村基, 小寺義男, 松下一之, 野村文夫]
通讯作者: 野村文夫
Comprehensive proteome analysis in search for biomarkers of hepatocellular carcinoma and its high risk group
综合蛋白质组分析寻找肝细胞癌及其高危人群的生物标志物
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Tagashira H, Fukunaga K, 野村文夫]
通讯作者: 野村文夫
DOI: 10.1111/j.1530-0277.2012.01883.x
发表时间: 2013
期刊: Alcoholism, clinical and experimental research
影响因子: --
作者: [M. Yamada;M. Satoh;Masanori Seimiya;K. Sogawa;S. Itoga;T. Tomonaga;F. Nomura]
通讯作者: M. Yamada;M. Satoh;Masanori Seimiya;K. Sogawa;S. Itoga;T. Tomonaga;F. Nomura
32
    Multidisciplinary modificomics to search for novel and early markers to detect hepatobiliary cancers
    • 批准号:
      25670266
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.5万
    • 财政年份:
      2013
    • 负责人:
      NOMURA Fumio
    • 依托单位:
    Development of early diagnostic markers for gastrointestinal and hepatobiliary cancers by multi-strategic proteome analyses
    • 批准号:
      19390154
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $12.48万
    • 财政年份:
      2007
    • 负责人:
      NOMURA Fumio
    • 依托单位:
    Comprehensive proteome analyses toward biomaker discovery for gastrointestinal and hepatobiliary cancers
    • 批准号:
      17590485
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.3万
    • 财政年份:
      2005
    • 负责人:
      NOMURA Fumio
    • 依托单位:
    Searches for novel tumor markers for gastrointestinal cancers by ProteinChip technology
    • 批准号:
      13672413
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.3万
    • 财政年份:
      2001
    • 负责人:
      NOMURA Fumio
    • 依托单位:
    海外基金