Development of new HPV vaccine for prevention of cervical cancer
Development of new HPV vaccine for prevention of cervical cancer
批准号:
22390309
负责人:
YOSHIKAWA Hiroyuki
金额:
$12.15万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
自然感染HPV16后产生的特异性中和抗体不利于HPV16诱导的低度宫颈病变的较好结果。在aa56到aa75区域至少有两个交叉中和表位,能够呈现这两个交叉中和表位的抗原将是一种很好的疫苗候选,用于广泛的高危HPV。
英文摘要
Development of specific neutralizing antibodies following natural HPV 16 infection did not favor a better outcome of low-grade cervical lesions induced by HPV 16. There are at least two cross-neutralization epitopes in the region from aa56 to aa75 and an antigen capable of presenting the two cross-neutralization epitopes would be a good vaccine candidate for a broad-spectrum of high-risk HPVs.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
ヒトパピローマウイルスワクチン
人乳头瘤病毒疫苗
DOI:
--
发表时间:
2010
期刊:
小児内科
影响因子:
--
作者:
[Tsukimori K, Fukushima K, Nakano H, Wake N, 吉川裕之]
通讯作者:
吉川裕之
広汎子宮全摘出(小林術式)
根治性子宫切除术(小林法)
DOI:
--
发表时间:
2010
期刊:
OGS Now(産婦人科手術シリーズ)
影响因子:
--
作者:
[Masumoto K, Teshiba R, Esumi G, Nagata K, Takahata Y, Hikino S, Hara T, Hojo S, Tsukimori K, Wake N, Kinukawa N, Taguchi T, 吉川裕之]
通讯作者:
吉川裕之
子宮頸がん治療の近未来展望 化学療法への期待と縮小手術
宫颈癌治疗的近期前景:化疗和缩小手术的期望
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Hayashi T, Horiuchi A, Sano K, Gur G, Aburatani H, Ishiko O, Yaegashi N, Shiozawa T, Kanai Y, Zharhary D, Tonegawa S, Konishi I., 吉川裕之]
通讯作者:
吉川裕之
HPVワクチンとHPV検査による子宮頸癌予防
通过 HPV 疫苗接种和 HPV 检测预防宫颈癌
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Hayashi T, Horiuchi A, Sano K, Gur G, Aburatani H, Ishiko O, Yaegashi N, Kanai Y, Zharhary D, Tonegawa S, Konishi I., 澤田 健二郎, 吉川裕之]
通讯作者:
吉川裕之
Efficacy of human papillomavirus 16/18 ASO4-adjuvanted vaccine in Japanese women aged 20 to 25 years : interim analysis of a phase 2 double-blind, randomized, controlled trial.
人乳头瘤病毒 16/18 ASO4 佐剂疫苗对 20 至 25 岁日本女性的功效:2 期双盲、随机、对照试验的中期分析。
DOI:
--
发表时间:
2010
期刊:
Int J Gynecol Cancer
影响因子:
4.8
作者:
[Konno R, Yoshikawa H, et al.]
通讯作者:
et al.
共 67 条
Experimental study of a novel fuel cell utilizing solar light and biomass
-
批准号:23656061
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.25万
-
财政年份:2011
-
负责人:YOSHIKAWA Hiroyuki
-
依托单位:
Development of biosensing technologies in an optical pickup style
-
批准号:23685016
-
项目类别:Grant-in-Aid for Young Scientists (A)
-
资助金额:$14.31万
-
财政年份:2011
-
负责人:YOSHIKAWA Hiroyuki
-
依托单位:
Clinical features of cervical cancer and type of human papillomavirus; especially the features and HPV18
-
批准号:23659770
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.33万
-
财政年份:2011
-
负责人:YOSHIKAWA Hiroyuki
-
依托单位:
Development of a prophylactic vaccine effective against a broader spectrum of HPVs associated with cervical cancer and basic research on therapeutic HPV vaccine for cervical cancer
-
批准号:19390424
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.81万
-
财政年份:2007
-
负责人:YOSHIKAWA Hiroyuki
-
依托单位:
Numerical Simulation of Three-Dimensional Separated Flowand Heat Transfer in Transient Reynolds Region
-
批准号:19560208
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.91万
-
财政年份:2007
-
负责人:YOSHIKAWA Hiroyuki
-
依托单位:
Study on development of HPV vaccine and the use for prevention of cervical cancer
-
批准号:16390472
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$8.83万
-
财政年份:2004
-
负责人:YOSHIKAWA Hiroyuki
-
依托单位:
Basic Research on development of HPV vaccine for prevention of cervical cancer
-
批准号:13470345
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.79万
-
财政年份:2001
-
负责人:YOSHIKAWA Hiroyuki
-
依托单位:
Immunological study for prevention and treatment of HPV-positive cervical cancer.
-
批准号:11671597
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.5万
-
财政年份:1999
-
负责人:YOSHIKAWA Hiroyuki
-
依托单位:
MOLECULAR EPIDEMIOLOGICAL STUDY FOR PREVENTION AND TREATMENT OF HPV-POSITIVE CERVICAL CANCER
-
批准号:08671872
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.47万
-
财政年份:1996
-
负责人:YOSHIKAWA Hiroyuki
-
依托单位:
Osteoporosis-evaluation with MR imaging-
-
批准号:08670993
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.34万
-
财政年份:1996
-
负责人:YOSHIKAWA Hiroyuki
-
依托单位:
Epidemiologic study on HPV infection for protecting generation of cervical cancer
-
批准号:06671630
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.28万
-
财政年份:1994
-
负责人:YOSHIKAWA Hiroyuki
-
依托单位:
Study on creation of science and technology, and its international flow・transfer.
-
批准号:01044168
-
项目类别:Grant-in-Aid for Overseas Scientific Survey.
-
资助金额:$0.0万
-
财政年份:1990
-
负责人:YOSHIKAWA Hiroyuki
-
依托单位:
Development of an Autonomous and Self Maintenance Machine
-
批准号:01550203
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.28万
-
财政年份:1989
-
负责人:YOSHIKAWA Hiroyuki
-
依托单位:
Theoretical Study on General Design Theory
-
批准号:60460096
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.35万
-
财政年份:1985
-
负责人:YOSHIKAWA Hiroyuki
-
依托单位:
海外基金