Osteoporosis-evaluation with MR imaging-

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Osteoporosis is characterized by demineralization of bone matrix, and T2^* will be prolonged due to diminution of susceptibility. The purpose of this study is to evaluate osteoporosis with MR imagint. MR images of the lumbar spine were obtained with gradient echo sequence. TR was 500 msec, and TEs were 4.5,9.3,14.1 (in phase), 6.9,11.7, and 16.5 msec (out of phase). Group A was consisted with 13 patients administered steroids for collagen disease, and group B was composed with 11 patients without steroids. T2^* was calculated from the decline of signal intensity - TE line. Mean T2^* values of patients with and without steroid therapy were 0.014 and 0.013, respectively, and there was no significant difference between these two groups. Bone matrix could not be evaluated with these methods.