Clarifying the metastatic mechanisms of melanoma by imaging techniques
Clarifying the metastatic mechanisms of melanoma by imaging techniques
批准号:
22390330
负责人:
FURUKAWA Hiroshi
金额:
$12.23万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
We reproduced melanoma in-transit metastasis (ITM) in a mouse hind limb by transplanting melanoma cells into the footpad of a mouse with lymphedema (LE). The tumor cells at the ITM site were highly proliferative, and mice with ITMs were more likely than control mice to develop distant lymph node and lung metastases. Peritumoral lymphatic vessels and tumor-associated blood vessels were increased in the primary tumor site of the LE mice.
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メラノーマin-transit転移の病態解明に関する動物実験第第2報~動物モデルを用いた性質の検討~
阐明黑色素瘤中转转移病理学的第二份动物实验报告 - 使用动物模型检查特性 -
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[木内貴博, 川名啓介, 大鹿哲郎, 大芦孝平]
通讯作者:
大芦孝平
A New Model of Acquired Lymphedema in the Mouse Hind Limb : A Preliminary Report of a Half-Year Course
小鼠后肢获得性淋巴水肿的新模型:半年病程的初步报告
DOI:
--
发表时间:
2011
期刊:
Annals of Plastic Surgery
影响因子:
1.5
作者:
[Nakano M, Ikeda Y, Mori K, Kinoshita S, Tashiro K, 他, Oshika T, Oashi Kohei]
通讯作者:
Oashi Kohei
メラノーマin-transit転移の動物実験モデル作成
黑色素瘤过境转移动物实验模型的建立
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Yokoi T, Toriyama N, Yamane T, Nakayama Y, Nishina S, Azuma N, 西村忠己,齋藤 修,宮前了輔,下倉良太,福田芙美,清水直樹,森本千裕,松井淑恵,細井裕司, 大芦孝平,古川洋志,山本有平]
通讯作者:
大芦孝平,古川洋志,山本有平
マウスリンパ節の構造と機能に関する検討とマウス後肢リンパ浮腫モデルの作成
小鼠淋巴结结构与功能研究及小鼠后肢淋巴水肿模型的建立
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[下倉良太, 高木悠哉, 西村忠己, 細井裕司, 東 範行, 大芦孝平,古川洋志,大澤昌之,山本有平]
通讯作者:
大芦孝平,古川洋志,大澤昌之,山本有平
メラノーマn-transit転移の病態解明に関する動物実験第2報~動物モデルを用いた性質の検討
阐明黑色素瘤过境转移病理学的第二份动物实验报告 - 使用动物模型检查特性
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Hiraoka T, Miyata K, Nakamura Y, Miyai T, Ogata M, Okamoto F, Oshika T, 大芦孝平,古川洋志,山本有平]
通讯作者:
大芦孝平,古川洋志,山本有平
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Development of non vascularized lymph node transfer by regulation of ECM
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批准号:20K09874
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The surgical lymphatic regeneration for improving the prognosis of melanoma
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资助金额:$10.65万
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Neurotization through the venous network in muscle : intravenous migration of Schwann cells.
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Effects of estrogen and selective estrogen receptor modulators on normal and keloid fibroblasts
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The regulation of the expression of SH2D1A gene in systemic lupus erythematosus.
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New lymphatic imaging with indocyanine green (ICG) dye labeled hyaluronic acid derivative
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Function-Based Adaptable Interface Design for Supporting MultipleAgent Operations with Different Types of Strategies
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Research of the development and the deodorizing capability of metal-pht halocyanine processed stump socket for amputees
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Function-Based Interface for Task Delegation in Human Supervision of an Agent Team
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Search for Novel Anti-cancer molecules from Plant Sources as Seeds of Possible Medicinal Agents.
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STUDY ON PATTERN FORMATION AND MORHOLOGICAL TRANSITION
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Immunohistochemical study for histamine in the retina of mammal
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Synthesis and Biochemical Properties of DNA-Intercalators using Natural Products as Lead Compounds.
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海外基金