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The BDNF pro-peptide is a novel facilitator of hippocampal LTD and the biological action is altered by a common BDNF polymorphism Val66Met

The BDNF pro-peptide is a novel facilitator of hippocampal LTD and the biological action is altered by a common BDNF polymorphism Val66Met
BDNF 前肽是海马 LTD 的新型促进剂,其生物作用因常见的 BDNF 多态性 Val66Met 而改变
批准号:
22500305
负责人:
KOJIMA Masami
金额:
$2.83万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

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中文摘要
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英文摘要
Most growth factors are initially synthesized as precursors and subsequently processed into their mature form and its pro-peptide by proteolytic cleavage in the secretory pathway and extracellular spaces. Compared to that of the mature form, the biologica
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ultiple functions of precursor BDNF to CNS neurons: negative regulation of neurite growth, spine formation and cell survival
前体 BDNF 对 CNS 神经元的多重功能:神经突生长、脊柱形成和细胞存活的负调节
DOI: --
发表时间: 2009
期刊: Mol. Brain
影响因子: --
作者: [Koshimizu, H., Kiyosue, K., Hara, T.,Hazama, S., Suzuki, S., Uegaki, K., Nagappan, G., Zaitsev, E., Hirokawa, T., Tatsu, Y., Ogura, A., Lu, B. & Kojima, M]
通讯作者: M
A novel role of the BDNF pro-peptide in the development of neuron : a new insight into neurotrophic hypothesis
BDNF 前肽在神经元发育中的新作用:对神经营养假说的新见解
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [Kodama M., Satoh Y., Otsubo Y., Araki Y., Yonamine R., Kazama T, T. Kozuka]
通讯作者: T. Kozuka
The BDNF pro-peptide is a novel facilitator of hippocampal LTD and the biological action is modulated by a common BDNF polymorphism Val66Met
BDNF 前肽是海马 LTD 的新型促进剂,其生物作用由常见的 BDNF 多态性 Val66Met 调节
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [Uegaki K., Ishikawa Y., Mizui T., Kumanogoh H., Kojima M]
通讯作者: Kojima M
BDNF and mood disorders
BDNF 和情绪障碍
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Kurioka T, Matsunobu T, Kurita A, Kamide D, Satoh Y, Kanzaki S, Ando T, Akiyama T, Sato S, Shiotani A, Masami Kojima]
通讯作者: Masami Kojima
18
    Does wearing of contact lens exacerbate millimeter wave exposure induced ocular disorder?
    • 批准号:
      15K12209
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.5万
    • 财政年份:
      2015
    • 负责人:
      KOJIMA Masami
    • 依托单位:
    3D ocular heat transfer analysis by infrared exposure
    • 批准号:
      23510068
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.58万
    • 财政年份:
      2011
    • 负责人:
      KOJIMA Masami
    • 依托单位:
    Route and defense of ultraviolet rays that invades interior of the eye back through glasses or sunglasses.
    • 批准号:
      20510055
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.0万
    • 财政年份:
      2008
    • 负责人:
      KOJIMA Masami
    • 依托单位:
    Functional analysis of BDNF protein using Proteomics techinology
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