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Development of quantum dot-based multimodal contrast agents for whole body imaging

Development of quantum dot-based multimodal contrast agents for whole body imaging
开发基于量子点的全身成像多模态造影剂
批准号:
22500407
负责人:
JIN Takashi
金额:
$2.91万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

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项目成果

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中文摘要
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英文摘要
The objective of this work was to develop multimodal contrast agents based on near-infrared (NIR) emitting quantum dots for whole body imaging. We could synthesis highly fluorescent near infrared emitting CdSeTe/CdS quantum dots with fluorescence quantum yield of > 50 %. Furthermore, we developed multimodal (NIR/MRI) contrast agents consisting of CdSeTe/CdS quantum dots and Fe_3O_4 nanoparticles and conducted dualmodal imaging of human breast tumors implanted to a nude mouse.
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DOI: 10.1073/pnas.1118472109
发表时间: 2012-04-03
期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
影响因子: 11.1
作者: [Ohmachi, Masashi, Komori, Yasunori, Yanagida, Toshio]
通讯作者: Yanagida, Toshio
Bioluminescence resonance energy transfer coupled near-infrared QDs using GST-tagged luciferase for in vivo imaging
使用 GST 标记的荧光素酶耦合近红外量子点的生物发光共振能量转移进行体内成像
DOI: --
发表时间: 2013
期刊: Chem. Commun
影响因子: --
作者: [Miyuki Hasegawa, Tsukasaki Yoshikazu, Tatsuya Ohyanagi and Takashi Jin]
通讯作者: Tatsuya Ohyanagi and Takashi Jin
DOI: 10.1016/j.bpj.2010.07.036
发表时间: 2010-10
期刊: Biophysical journal
影响因子: 3.4
作者: [Tomonobu M. Watanabe;S. Fukui;T. Jin;F. Fujii;T. Yanagida]
通讯作者: Tomonobu M. Watanabe;S. Fukui;T. Jin;F. Fujii;T. Yanagida
蛍光性半導体ナノ粒子(量子ドット)の合成、表面修飾とその医療応用
荧光半导体纳米粒子(量子点)的合成、表面修饰及其医学应用
DOI: --
发表时间: 2010
期刊: 粉体工学会誌 47
影响因子: --
作者: [静野 眞, 稲葉 稔, 宇野 雅晴, 錦 善則, 古田 常人, 田坂 明政, 神隆]
通讯作者: 神隆
25
    Development of fluorescent probes based on calixarene-coated water soluble quantum dots
    • 批准号:
      19550157
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.0万
    • 财政年份:
      2007
    • 负责人:
      JIN Takashi
    • 依托单位:
    Photocontrol of ion flux across a lipid bilayer membrane by visible light
    • 批准号:
      15550142
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.37万
    • 财政年份:
      2003
    • 负责人:
      JIN Takashi
    • 依托单位:
    Fluorescence Determination of Optical Purity of Aminoacid Ester using Fluorescence Labeled Chiral Host Molecules
    • 批准号:
      06640771
    • 项目类别:
      Grant-in-Aid for General Scientific Research (C)
    • 资助金额:
      $1.28万
    • 财政年份:
      1994
    • 负责人:
      JIN Takashi
    • 依托单位:
    Synthesis and Application of Ion Recognition Compounds with High Sensitivities for Medical Science
    • 批准号:
      04557112
    • 项目类别:
      Grant-in-Aid for Developmental Scientific Research (B)
    • 资助金额:
      $2.5万
    • 财政年份:
      1992
    • 负责人:
      JIN Takashi
    • 依托单位: