Stem cell culture system with immobilized signal proteins.
Stem cell culture system with immobilized signal proteins.
批准号:
22500431
负责人:
KITAJIMA Takashi
金额:
$2.5万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
Various signal proteins such as cytokines and growth factors were photo-immobilized on culture vessels to investigate the effect of them on stem cells. Immobilized LIF and MCP1 chemokine grow ES cells in undifferentiated state. Activin-A immobilized at high dose enhanced ES cells to differentiate into endodermal cells, and at lower dose to cells with mesodermal phenotype. Immobilized VEGF grow CD31 positive cells directly from mouse iPS cells without prior sorting of differentiating cells. These results suggest the possibility of culture devices for stem cells that can regulate differentiation.
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DOI:
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发表时间:
2010
期刊:
影响因子:
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作者:
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发表时间:
2010
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[Atsushi Koriyama, Wataru Yasuhara, Hiroyuki Hachiya, 姜 廷和 櫻木 誠 阿部 洋 北嶋 隆]
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姜 廷和 櫻木 誠 阿部 洋 北嶋 隆
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发表时间:
2010
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Chapter 17. Artificial Binding Growth Factors. In Handbook of Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine
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DOI:
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发表时间:
2012
期刊:
影响因子:
--
作者:
[Kitajima, T., and Ito, Y]
通讯作者:
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DOI:
10.1016/j.msec.2012.07.039
发表时间:
2012-12-01
期刊:
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
影响因子:
7.9
作者:
[Kang, Jeonghwa, Sakuragi, Makoto, Ito, Yoshihiro]
通讯作者:
Ito, Yoshihiro
共 29 条
Biomaterials combined with Engineered Growth Factors with collagen binding affinity for tissue regeneration.
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批准号:18500371
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.96万
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财政年份:2006
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负责人:KITAJIMA Takashi
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依托单位:
海外基金