Exercise therapy for hypertension and diabetes mellitus: involvement of cross-adaptation to stress via inhibition of sympathetic nervous system

我们研究了4周跑步训练对自发性高血压大鼠（SHR）应激（固定应激）引起的血压（BP）和儿茶酚胺水平升高的影响。研究了大鼠对外源性去甲肾上腺素（NE）的敏感性。目前的研究结果表明，在4周的跑步训练后，交感神经系统的应激激活和对NE的敏感性都减弱了，从而降低了对新应激的血压反应。

We investigated effects of 4-weeks’ running training on the increases in blood pressure (BP) and catecholamine levels induced by a novel stress (immobilization stress) in spontaneously hypertensive rats (SHR). The rats’ sensitivity to exogenously infused norepinephrine (NE) was investigated too. The present results suggest that the stress-induced activation of the sympathetic nervous system and the sensitivity to NE were each attenuated after 4-weeks’ running training, with a consequent reduction in the BP response to a novel stress.