Visceral fat inspection method based on the ultrasound tomographic reconstruction of abdominal tissue sound speed image

基于腹部组织声速图像超声断层重建的内脏脂肪检查方法

• 批准号: 22560414
• 负责人: YAMADA Akira
• 金额: $ 2.91万
• 依托单位: Tokyo University of Agriculture and Technology
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22560414/
• 关键词: 計測システム; 音波トモグラフィ; 内蔵脂肪検査; 超音波腹部スキャナー; 腹部断面音速分布映像; 超音波CT; 超音波画像診断; 超音波トモグラフィ; 医用超音波画像診断; 内蔵脂肪症診断; 音波伝搬時間測定; 生体組織音速の映像化; 計算機画像再構成; 人体腹部断面の可視化; 生体弾性物理量計測; 内臓脂肪症(メタボリック症)診断; 生体組織音速分布の映像化; 生体弾性物理量の非侵襲計測

In the present study, investigations and validation experiments were made for the realization of acoustic tomographic visceral fat inspection apparatus based on the observation of ultrasound time of flight data around human abdominal surface. In particular, mechanical scanning system using a facing pair of high sensitivity broad band piezoelectric transducers in low frequency range was developed, so that waves propagated through the long distant intestinal gaseous medium can be detected without suffering sound attenuation. In addition, urethane gel hemi-spheres were attached in front of the transducers to keep good contact between transducer and body surface, regardless of contact angles between them. The facing pair transducers attached on the automated actuator stages for the movement of rotation (720 mm in diameter), translation (600 mm stroke), and pushing (300 mm stroke) were controlled by the computers to move to arbitral positions on the abdominal body surface. On this occasion, … More to minimize the loss of data caused by the avoidance of sound propagation paths intersecting a spine, propagation path was determined so that center of scanning rotation was adjusted to the spine. To this end, contour of the body surface was measured by laser range sensor and spine position was estimated in advance. By this means, the paths were adaptively determined in accordance with patient’s body size and sitting position. In addition, amplitudes of the sound waves were monitored so that contact condition can be controlled at an optimalpushing position regardless of the deviation of the premeasured body surface position. Finally, from the evaluation experiments by using the phantom specimen, it was shown that the measured precision of time of flight data were good enough to reproduce the abdominal sound speed cross sectional profile image. In addition, validity of the proposed visceral fat measurement techniques was confirmed from the results that fat areas can be clearly discriminated from the remaining protein areas with high degree of accuracy. Although the evaluation experiments for human patients were remained as future work, the system was brought to completion which can automatically collect the sound wave data around body surface andmeasure the visceral fat area from the abdominal reconstructed sound speed image. Less

本研究针对基于人体腹部表面超声飞行时间数据观测的声学断层内脏脂肪检查仪的实现进行了研究和验证实验。特别是，开发了在低频范围内使用一对面对面的高灵敏度宽带压电换能器的机械扫描系统，使得可以在不遭受声音衰减的情况下检测到通过长距离肠道气体介质传播的波。此外，聚氨酯凝胶半球附在换能器前面，以保持换能器和身体表面之间的良好接触，无论它们之间的接触角如何。连接在自动执行器平台上的面向传感器对用于旋转（直径 720 毫米）、平移（600 毫米行程）和推动（300 毫米行程）的运动，由计算机控制移动到腹部体表面的任意位置。在这种情况下，为了最大限度地减少由于避免声音传播路径与脊柱相交而造成的数据丢失，确定了传播路径，以便将扫描旋转中心调整到脊柱。为此，通过激光测距传感器测量身体表面的轮廓，并提前估计脊柱位置。通过这种方式，根据患者的体型和坐姿自适应地确定路径。此外，还监测声波的振幅，以便无论预先测量的体表位置是否存在偏差，都可以将接触条件控制在最佳的推动位置。最后，通过使用模型标本的评估实验表明，飞行时间数据的测量精度足以再现腹部声速横截面轮廓图像。此外，结果证实了所提出的内脏脂肪测量技术的有效性，即可以以高精度将脂肪区域与剩余蛋白质区域清楚地区分开。虽然对人体患者的评估实验仍待后续工作，但该系统已经完成，可以自动收集体表周围的声波数据，并从腹部重建的声速图像中测量内脏脂肪面积。较少的

项目成果

「Quasi real time monitoring system for the tomographic reconstruction of the vortex wind field」

《涡旋风场层析重建准实时监测系统》

• 发表时间: 2012
• 作者: Haiyue Li;Takuya Hirasawa and Akira Yamada
• 通讯作者: Takuya Hirasawa and Akira Yamada

Body Surface Automated Mechanical Scanner for the Abdominal Sound Speed Tomographic Imaging

用于腹部声速断层成像的体表自动机械扫描仪

• 发表时间: 2013
• 作者: T. Yoyama;K. Sasaki;D.Shimizu;H. Li and A.Yamada
• 通讯作者: H. Li and A.Yamada

体表上走査腹部組織音速トモグラフィ映像の再現性能向上のための検討

提高体表扫描腹部组织声波断层扫描图像再现性能的研究

• 发表时间: 2011
• 作者: 和田;山田;島袋;坂野
• 通讯作者: 坂野

Closely-contact body surface scanning mechanism for the acoustic tomographic measurement of the visceral fat area

用于内脏脂肪面积声学断层测量的紧密接触体表扫描机构

• 发表时间: 2011
• 作者: T.Shimabukuro;K.Sasaki;T.Yokoyama;A.Yamada
• 通讯作者: A.Yamada

生体組織音速の非侵襲音波トモグラフィ計測

无创声学断层扫描测量活体组织中的声速