Analysis of vascular remodeling by t-PA/t-PAR system
Analysis of vascular remodeling by t-PA/t-PAR system
批准号:
22590219
负责人:
MATSUO Osamu
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
t-PAR-transfected endothelial cells enhanced the t-PA binding ability, t-PA-mediated plasminogen activation, migration and invasion of cells, and tube formation as compared with control endothelial cells. Vascular smooth muscle cells bound to t-PA and enhanced t-PA-mediated plasminogen activation. Therefore, it is thought that t-PA/t-PAR system on the membrane surface of these cells plays an important role on the tissue regeneration process.
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DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[岡田清孝, 上嶋 繁, 河尾直之, 永井信夫, 松尾 理]
通讯作者:
松尾 理
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DOI:
--
发表时间:
2011
期刊:
影响因子:
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作者:
[勇井克也, 山下里奈, 上嶋繁]
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Enhancement o nno ytic activity in vascular endothelial cells by heterologous expression of adenine nucleotide translocase-1.
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DOI:
--
发表时间:
2010
期刊:
Blood Coagulation and Fibrinolysis
影响因子:
1.1
作者:
[Shimizu T, Tashiro-Yamaji J, Hayashi M, Inoue Y, Ibata M, Kubota T, Tanigawa N, Yoshida R, Chikako Ishida]
通讯作者:
Chikako Ishida
The mechanism of enhancement on plasminogen activation and thrombolysis by synthetic nonadecapeptide.
合成九肽增强纤溶酶原激活和溶栓作用的机制。
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Okada K, Ueshima S, Matsuno H, Kawao N, Tamura Y, Yano M, Nagai N, Matsuo O]
通讯作者:
Matsuo O
Impaired accumulation of macrophages and absence of their phenotype heterogeneity during liver repair in urokinase-deficient mice.
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DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Kawao N, Nagai N, Tamura Y, Okumoto K, Okada K, Yano M, Suzuki Y, Umemura K, Ueshima S, Matsuo O.]
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Matsuo O.
共 16 条
Analysis of regulation by t-PA/t-PAR-mediate protease on regeneration system after tissue damage
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批准号:19590217
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2007
-
负责人:MATSUO Osamu
-
依托单位:
Analysis of biological function by t-PA receptor gene expression regulation
-
批准号:17590193
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.18万
-
财政年份:2005
-
负责人:MATSUO Osamu
-
依托单位:
Expression of t-PA receptor on the endothelial cell and analysis of its physiological function.
-
批准号:15590198
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
-
财政年份:2003
-
负责人:MATSUO Osamu
-
依托单位:
Analysis of the mechanism of angiogenesis regulated by fibrinolytic factors
-
批准号:13670049
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.24万
-
财政年份:2001
-
负责人:MATSUO Osamu
-
依托单位:
Analysis of the biological function of vascular smooth muscle cells regulated by fibrinolytic factors
-
批准号:11670054
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.24万
-
财政年份:1999
-
负责人:MATSUO Osamu
-
依托单位:
Analysis of angiogenesis in fibrinolytic factordefficient mice
-
批准号:09670062
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.86万
-
财政年份:1997
-
负责人:MATSUO Osamu
-
依托单位:
海外基金