Analysis of positive selection process during T eell development via large transcription factor
Analysis of positive selection process during T eell development via large transcription factor
批准号:
22590443
负责人:
TAKAGI Tsuyoshi
金额:
$2.91万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
Our bodies are protected from foreign bodies with sophisticated immune system. Establishment of acquired immune system should be highly regulated. Because destruction of this process means that ourselves might be exposed to attack from our immune cells. It is very important to understand how suitable T cells are selected to develop. In this study, I revealed how the transcription factor, that is essential for this process, regulates downstream genes to achieve it.
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DOI:
10.1038/nature09848
发表时间:
2011-04-07
期刊:
NATURE
影响因子:
64.8
作者:
[Staton, Tracy L., Lazarevic, Vanja, Jones, Dallas C., Lanser, Amanda J., Takagi, Tsuyoshi, Ishii, Shunsuke, Glimcher, Laurie H.]
通讯作者:
Glimcher, Laurie H.
Deficiency of Schnurri-2, a MHC enhancer binding protein, induce mild chronic inflammation in the brain and confers molecular, neuronal, and behavioral phenotypes related to schizopherenia
Schnurri-2(一种 MHC 增强子结合蛋白)的缺乏会诱发大脑中的轻度慢性炎症,并导致与精神分裂症相关的分子、神经元和行为表型
DOI:
--
发表时间:
2013
期刊:
Neuropsychopharmacology
影响因子:
7.6
作者:
[Keizo Takao, Katsunori Kobayashi, Hideo Hagihara, Koji Ohira, Hirotaka Shoji, Satoko Hattori, Hisatsugu Koshimizu, Juzoh Umemori, Keiko Toyama, Hironori K Nakamura, Mahomi Kuroiwa, Jun Maeda, Kimie Atsuzawa, Kayoko Esaki, Shun Yamaguchi, Shigeki Furuya, T]
通讯作者:
T
Positive selectionに必要なSchnurr-2のchip on chip法を用いた解析
使用正选所需的 Schnurr-2 芯片上芯片方法进行分析
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Okuzaki D, Fukushima T, Tougan, T, Ishii T, Kobayashi S, Yoshizaki K, Akita T, Nojima H., 高木豪,石井俊輔]
通讯作者:
高木豪,石井俊輔
de novo型Sip1ヘテロ変異マウスを用いたMowat-Wilson syndromeのモデル動物としての有用性の検討
检查从头 Sip1 杂合突变小鼠作为 Mowat-Wilson 综合征模型动物的有用性
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[高木豪, 東雄二郎]
通讯作者:
東雄二郎
Chip on chip analysis of transcription factor, Schnurri-2 using DP cells.
使用 DP 细胞对转录因子 Schnurri-2 进行芯片上芯片分析。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[高木豪, 石井俊輔]
通讯作者:
石井俊輔
Security Analysis of Public-Key Cryptography by Large-Scale Experiments
-
批准号:22650014
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.09万
-
财政年份:2010
-
负责人:TAKAGI Tsuyoshi
-
依托单位:
Mathematical Foundation and Implantation Methods for Pairing-Based Cryptography
-
批准号:22300026
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$8.74万
-
财政年份:2010
-
负责人:TAKAGI Tsuyoshi
-
依托单位:
Efficiency Analysis of Arithmetic for Public-Key Cryptosystems and its Applications
-
批准号:18500015
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.53万
-
财政年份:2006
-
负责人:TAKAGI Tsuyoshi
-
依托单位:
海外基金