Investigation of ambulatory arterial stiffness index as a risk factor of cardiovascular disease

动态动脉僵硬度指数作为心血管疾病危险因素的研究

• 批准号: 22590767
• 负责人: KIKUYA Masahiro
• 金额: $ 2.83万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22590767/
• 关键词: 動脈硬化; ABPM; 心血管病; AASI; 血圧測定; HASI

Ambulatory arterial stiffness index (AASI) is an index of arterial stiffness and can be computed from ambulatory blood pressure (ABP) recordings. We found that (1) decrease in number of readings in ABP does not affect predictive accuracy of AASI for cardiovascular mortality, until the median number of readings per ABP recording is less than 35, (2) AASI computed by home blood pressure predicted cerebral infarction, (3) and had weak association with intima-media thickness of carotid artery.

动态动脉僵硬指数(AASI)是动脉僵硬的一个指标，可以根据动态血压(ABP)记录来计算。我们发现(1)ABP读数的减少不会影响AASI对心血管死亡率的预测准确性，除非每个ABP记录的读数的中位数小于35，(2)根据家庭血压计算的AASI预测脑梗塞，(3)AASI与颈动脉内膜-中层厚度的相关性较弱。

项目成果

Predictive Value for Mortality of the Double Product at Rest Obtained by Home Blood Pressure Measurement: The Ohasama Study

• DOI: 10.1038/ajh.2012.3
• 发表时间: 2012-05-01
• 期刊: AMERICAN JOURNAL OF HYPERTENSION
• 影响因子: 3.2
• 作者: Inoue, Ryusuke;Ohkubo, Takayoshi;Imai, Yutaka
• 通讯作者: Imai, Yutaka

Home Blood Pressure Level, Blood Pressure Variability, Smoking, and Stroke Risk in Japanese Men: The Ohasama Study

• DOI: 10.1038/ajh.2012.62
• 发表时间: 2012-08-01
• 期刊: AMERICAN JOURNAL OF HYPERTENSION
• 影响因子: 3.2
• 作者: Hashimoto, Takanao;Kikuya, Masahiro;Imai, Yutaka
• 通讯作者: Imai, Yutaka

Aldosterone-to-Renin Ratio as a Predictor of Stroke Under Conditions of High Sodium Intake : The Ohasama Study

高钠摄入条件下醛固酮与肾素比率作为中风的预测因子：Ohasama 研究

• DOI: 10.1038/ajh.2012.33
• 发表时间: 2012
• 期刊: Am J Hypertens
• 影响因子: 3.2
• 作者: Satoh M;Kikuya M;Ohkubo T;Mori T;Metoki H;Hara A;Utsugi MT;Hashimoto T;Hirose T;Obara T;Inoue R;Asayama K;Kanno A;Totsune K;Hoshi H;Satoh H;Imai Y.
• 通讯作者: Imai Y.

家庭血圧によるHome Arterial Stiffness Index(HASI)と頸動脈病変との関連:大迫研究

由家庭血压确定的家庭动脉僵硬指数 (HASI) 与颈动脉病变之间的关系：Osako 研究

• 发表时间: 2011
• 作者: Otsuka K;Matsumoto H;et al;菊谷昌浩
• 通讯作者: 菊谷昌浩

(Total 11, 2nd) Validation of the FM-800 Ambulatory Blood Pressure Monitor According tothe Association for the Advancement of Medical Instrumentation Criteria and the International Protocol

（共 11、第 2） FM-800 动态血压监测仪根据医疗仪器标准促进协会和国际协议进行验证

• DOI: 10.3109/10641963.2010.496513
• 发表时间: 2010
• 期刊: Clin Exp Hypertens
• 影响因子: 12.3
• 作者: Nakamura K;Kikuya M;Hara A;Hirose T;Imai Y et al
• 通讯作者: Imai Y et al