Strategy for hypoxic-ischemic encephalopathy in newborn infants to reduce oxygen free radicals by adjusting hydrogen and oxygen
Strategy for hypoxic-ischemic encephalopathy in newborn infants to reduce oxygen free radicals by adjusting hydrogen and oxygen
批准号:
22591201
负责人:
KUSAKA Takashi
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
In these studies, we found that combining the cerebral blood volume (CBV) with amplitude-integrated EEG (aEEG) is a more effective guide to control hypoxic/ischemic (HI) insult in a newborn piglet model than aEEG alone, to produce a consistent degree of survivable neuropathological damage. Next, we found that an early CBV increase and longer low-ampitude EEG after insult indicates severe brain injury. Finally, we revealed that Edaravone (a free radical scavenger) reduced histologic neuronal damage related to HI loading in our piglet HI model.
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近赤外光を利用した新生児の脳循環・代謝評価
利用近红外光评估新生儿脑循环和代谢
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Shimtada A, Hayashi Y, et. al., 日下隆]
通讯作者:
日下隆
A founder effect of c.1938delC in ITGB4 underlies junctional epidermolysis bullosa and its application for prenatal testing
c.1938delC 在 ITGB4 中的创始人效应是交界性大疱性表皮松解症及其在产前检测中的应用的基础
DOI:
--
发表时间:
2011
期刊:
Exp Dermatol
影响因子:
3.6
作者:
[Natsuga K, Nishie W, Shinkuma S, Nakamura H, Arita K, Yoneda K, Kusaka T, Yanagihara T, Kosaki R, Sago H, Akiyama M, Shimizu H]
通讯作者:
Shimizu H
新生仔豚仮死モデルによる低酸素負荷後早期の脳循環の検討(第2 報)-脳血液量と aEEG の関係
新生仔猪窒息模型低氧负荷后早期脑循环检查(第二报告)——脑血容量与aEEG的关系
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[中村信嗣, 神内済, 國方淳, 小谷野耕佑, 中村信, 安田真之, 日下隆, 磯部健一, 伊藤進]
通讯作者:
伊藤進
新生仔豚仮死モデルによる低酸素負荷後早期の脳循環の検討(第2報)-脳血液量とaEEGの関係
新生仔猪窒息模型低氧负荷后早期脑循环检查(第二报告)——脑血容量与aEEG的关系
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[中村信嗣, ら]
通讯作者:
ら
新生仔豚を用いた急性貧血モデルにおける脳循環の代償性変化
新生仔猪急性贫血模型脑循环的代偿性变化
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[小谷野耕佑, 小谷野薫, 伊地知園子, 加藤育子, 小西行彦, 久保井徹, 大久保賢介, 安田真之, 日下隆, 磯部健一, 伊藤進]
通讯作者:
伊藤進
共 46 条
Developmental changes in cerebral oxygen metabolism during neonatal period
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批准号:19591281
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2007
-
负责人:KUSAKA Takashi
-
依托单位:
New optical brain imaging in infants by using near-infrared diffuse optical tomography
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批准号:17390307
-
项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$5.82万
-
财政年份:2005
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负责人:KUSAKA Takashi
-
依托单位:
Estimation of the temporal and spatial distribution of the optically thin Asian dust from satellite image data
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批准号:16510011
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
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财政年份:2004
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负责人:KUSAKA Takashi
-
依托单位:
Noninvasive optical imaging in the sensorimotor cortex in newborn infants.
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批准号:15591159
-
项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
-
财政年份:2003
-
负责人:KUSAKA Takashi
-
依托单位:
The estimation of the advection diffusion and the optical characteristics of the Asian dust using satellite_level data
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批准号:13680611
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$0.58万
-
财政年份:2001
-
负责人:KUSAKA Takashi
-
依托单位:
Evaluation of Yellow Sand Dust in the Vegetation Index Estimated from Satellite-level Data
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批准号:10680508
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
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财政年份:1998
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负责人:KUSAKA Takashi
-
依托单位:
The development of the hypermedia CAI system on the Internet
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批准号:07558146
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$0.64万
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财政年份:1995
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负责人:KUSAKA Takashi
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依托单位:
Extraction of Global Environmental Change caused by Human Activities
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批准号:04832042
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1992
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负责人:KUSAKA Takashi
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依托单位:
海外基金