Basic studies on therapeutic utilities ofIL-27 for malignant melanoma, psoriasis and alopecia areata.
Basic studies on therapeutic utilities ofIL-27 for malignant melanoma, psoriasis and alopecia areata.
批准号:
22591220
负责人:
NAGAI Hiroshi
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
We conducted studies on therapeutic effects of interleukin (IL)-27 on malignant melanoma and psoriasis in murine models. We also examined the effects ofIL-27 on chemokine production from human epidermal keratinocytes and demonstrated that IL-27 and IL-17 exerted opposite effects on tumor necrosis factor-alpha-mediated psoriasis relatedchemokine production.
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皮膚科臨床アセット 11
皮肤科临床资产 11
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Susumu Fujiwara, Hiroshi Nagai, Shuntaro Oniki, Takayuki Yoshimoto, and Chikako Nishigori, 永井 宏]
通讯作者:
永井 宏
IL-17 versus IL-27 : Opposite effects on TNF-α-induced chemokine production in human keratinocytes
IL-17 与 IL-27:对 TNF-α 诱导的人角质形成细胞中趋化因子产生的相反作用
DOI:
--
发表时间:
2012
期刊:
Experimental Dermatology
影响因子:
3.6
作者:
[Fujiwara S, Nagai H, Oniki S, Yoshimoto T, Nishigori C]
通讯作者:
Nishigori C
IL-17 versus IL-27: Opposite effects on tumor necrosis factor-alpha-mediated chemokine production in human keratinocytes
IL-17 与 IL-27:对人角质形成细胞中肿瘤坏死因子-α 介导的趋化因子产生的相反作用
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Susumu Fujiwara, Hiroshi Nagai, Shuntaro Oniki, Takayuki Yoshimoto, and Chikako Nishigori]
通讯作者:
and Chikako Nishigori
IL-23 gene therapy for mouse bladder tumor cell lines.
针对小鼠膀胱肿瘤细胞系的 IL-23 基因治疗。
DOI:
--
发表时间:
期刊:
BJU Int. (in press)
影响因子:
--
作者:
[Kuramoto T., Fujii R., Nagai H., Belladonna M.L., Yoshimoto T., Kohjimoto Y., Inagaki T., Hara I.]
通讯作者:
Hara I.
Antimelanoma immunotherapy: clinical and preclinical applications of IL-12 family members
抗黑色素瘤免疫疗法:IL-12家族成员的临床和临床前应用
DOI:
10.2217/imt.10.46
发表时间:
2010
期刊:
Immunotherapy.
影响因子:
--
作者:
[H. Nagai, S. Oniki, S. Fujiwara, T. Yoshimoto, and C. Nishigori]
通讯作者:
and C. Nishigori
共 7 条
Evaluation of Bearing Capacity of New Piles Considering Construction History
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批准号:18K04421
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
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财政年份:2018
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负责人:NAGAI Hiroshi
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依托单位:
Evaluation on seismic response of piled raft foundation considering soil-structure interaction
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批准号:16K18180
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$1.75万
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财政年份:2016
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负责人:NAGAI Hiroshi
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依托单位:
Searching for novel compounds from the nematocysts.
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批准号:24510294
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.49万
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财政年份:2012
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负责人:NAGAI Hiroshi
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依托单位:
Effect of Cross-sex Hormones on Cognitive Abilities and the Psychological Characteristics of Gender Identity Disorder
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批准号:21791155
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$1.33万
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财政年份:2009
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负责人:NAGAI Hiroshi
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依托单位:
The development of novel bioactive compounds from the nematocysts.
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批准号:20510197
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
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财政年份:2008
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负责人:NAGAI Hiroshi
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依托单位:
The Study on Proteinaceous Toxins from the Cnidarians.
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批准号:15510172
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2003
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负责人:NAGAI Hiroshi
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依托单位:
Structure and Function of Proteinaceous Toxins from Marine Animals
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批准号:12045267
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$8.19万
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财政年份:2000
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负责人:NAGAI Hiroshi
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依托单位:
Chemical and biochemical study on venomous jellyfish proteinaceous toxins
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批准号:11660210
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:1999
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负责人:NAGAI Hiroshi
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依托单位:
Improvement and Practical Application of FeSi_2 Thermoelectric Materials with Dispersion of Fine Particles by Liquid Phase Sintering.
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批准号:10555248
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$7.87万
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财政年份:1998
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负责人:NAGAI Hiroshi
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依托单位:
Improvement Mechanism of Thermoelectric Materials by Dispersion of Fine Particles.
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批准号:09450273
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$6.78万
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财政年份:1997
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负责人:NAGAI Hiroshi
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依托单位:
Development and Mechanism of High Performance Thermoelectric Materials by Dispersion of Fine Particles
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批准号:07455289
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.93万
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财政年份:1995
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负责人:NAGAI Hiroshi
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依托单位:
Development and Application of High Performance Thermoelectric Materials by Powder Metallurgical Procedure Using Mechanical Alloying.
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批准号:06555212
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$9.02万
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财政年份:1994
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负责人:NAGAI Hiroshi
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依托单位:
Preparation and Properties of Thermoelectric Materials by PM Process.
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批准号:03650554
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.41万
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财政年份:1991
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负责人:NAGAI Hiroshi
-
依托单位:
海外基金