Early prediction of therapeutic effect of molecular targeting therapy for solid malignant tumor with imaging biomarkers

点击翻译按钮获取中文摘要

Dilatation of intratumoral vessels on multiphasic contrast enhanced CT was estimated to be one of the key findings for prediction of early therapeutic effect evaluation of molecular-targeting therapy for hepatocellular carcinoma (HCC). There are no significant correlation between hemodynamic parameters of CT perfusion just after starting of molecular-targeting therapy for HCC and long term therapeutic effect of it. In contrast, intratumoral iodine measurement obtained by dual-energy CT technique might be used as surrogate marker for early prediction of therapeutic effect of molecular targeting therapy for HCC.